Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Adipose-Tissue.Adipose-Tissue.cls #Adipose-Tissue_20-29_versus_Adipose-Tissue_30-39.Adipose-Tissue.cls #Adipose-Tissue_20-29_versus_Adipose-Tissue_30-39_repos |
| Phenotype | Adipose-Tissue.cls#Adipose-Tissue_20-29_versus_Adipose-Tissue_30-39_repos |
| Upregulated in class | Adipose-Tissue_30-39 |
| GeneSet | GOBP_BONE_RESORPTION |
| Enrichment Score (ES) | -0.5240184 |
| Normalized Enrichment Score (NES) | -1.5384202 |
| Nominal p-value | 0.044036698 |
| FDR q-value | 0.81811416 |
| FWER p-Value | 0.946 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | PPARGC1B | NA | 781 | 0.186 | 0.0120 | No |
| 2 | UBASH3B | NA | 1503 | 0.148 | 0.0197 | No |
| 3 | NCDN | NA | 2428 | 0.121 | 0.0198 | No |
| 4 | TNFSF11 | NA | 3647 | 0.099 | 0.0114 | No |
| 5 | ITGB3 | NA | 3666 | 0.099 | 0.0250 | No |
| 6 | CALCA | NA | 4069 | 0.093 | 0.0307 | No |
| 7 | TFRC | NA | 4336 | 0.089 | 0.0384 | No |
| 8 | IL6 | NA | 5959 | 0.070 | 0.0186 | No |
| 9 | MC4R | NA | 6389 | 0.066 | 0.0200 | No |
| 10 | FSHB | NA | 6522 | 0.065 | 0.0267 | No |
| 11 | CA2 | NA | 7875 | 0.053 | 0.0094 | No |
| 12 | IAPP | NA | 8822 | 0.045 | -0.0016 | No |
| 13 | SRC | NA | 8890 | 0.045 | 0.0035 | No |
| 14 | ADAM8 | NA | 10986 | 0.030 | -0.0306 | No |
| 15 | TNFAIP3 | NA | 13568 | 0.016 | -0.0757 | No |
| 16 | TF | NA | 14568 | 0.011 | -0.0924 | No |
| 17 | CARTPT | NA | 16524 | 0.004 | -0.1277 | No |
| 18 | IHH | NA | 28575 | -0.028 | -0.3447 | No |
| 19 | TNFRSF11B | NA | 30053 | -0.035 | -0.3668 | No |
| 20 | SNX10 | NA | 30506 | -0.037 | -0.3699 | No |
| 21 | ADRB2 | NA | 30882 | -0.039 | -0.3713 | No |
| 22 | CD38 | NA | 31999 | -0.045 | -0.3854 | No |
| 23 | IL20RA | NA | 32149 | -0.045 | -0.3818 | No |
| 24 | CSK | NA | 32187 | -0.046 | -0.3760 | No |
| 25 | S1PR1 | NA | 32415 | -0.047 | -0.3736 | No |
| 26 | PDK4 | NA | 33662 | -0.053 | -0.3890 | No |
| 27 | BGLAP | NA | 34810 | -0.059 | -0.4017 | No |
| 28 | HAMP | NA | 36905 | -0.070 | -0.4302 | No |
| 29 | TMEM64 | NA | 39266 | -0.084 | -0.4617 | No |
| 30 | PTH | NA | 40626 | -0.092 | -0.4736 | No |
| 31 | IL7 | NA | 41974 | -0.100 | -0.4842 | No |
| 32 | NF1 | NA | 41991 | -0.100 | -0.4703 | No |
| 33 | PLEKHM1 | NA | 44919 | -0.121 | -0.5070 | Yes |
| 34 | EGFR | NA | 44979 | -0.121 | -0.4910 | Yes |
| 35 | INPP5D | NA | 45188 | -0.123 | -0.4776 | Yes |
| 36 | TNFRSF11A | NA | 46064 | -0.129 | -0.4754 | Yes |
| 37 | CLDN18 | NA | 46091 | -0.129 | -0.4576 | Yes |
| 38 | CSF1R | NA | 46225 | -0.130 | -0.4416 | Yes |
| 39 | TPP1 | NA | 46288 | -0.131 | -0.4243 | Yes |
| 40 | DEF8 | NA | 46671 | -0.134 | -0.4124 | Yes |
| 41 | GPR137B | NA | 47294 | -0.139 | -0.4041 | Yes |
| 42 | DCSTAMP | NA | 47471 | -0.141 | -0.3874 | Yes |
| 43 | SPP1 | NA | 47635 | -0.142 | -0.3703 | Yes |
| 44 | RAC1 | NA | 47753 | -0.144 | -0.3522 | Yes |
| 45 | SIGLEC15 | NA | 48294 | -0.148 | -0.3412 | Yes |
| 46 | LRRK1 | NA | 48323 | -0.149 | -0.3207 | Yes |
| 47 | SYK | NA | 48916 | -0.154 | -0.3099 | Yes |
| 48 | PTK2B | NA | 49003 | -0.155 | -0.2896 | Yes |
| 49 | RAC2 | NA | 49553 | -0.160 | -0.2770 | Yes |
| 50 | PRKCA | NA | 50036 | -0.165 | -0.2625 | Yes |
| 51 | GPR137 | NA | 50076 | -0.166 | -0.2398 | Yes |
| 52 | GPR55 | NA | 50167 | -0.167 | -0.2179 | Yes |
| 53 | ACP5 | NA | 50834 | -0.175 | -0.2055 | Yes |
| 54 | LTBP3 | NA | 51143 | -0.179 | -0.1859 | Yes |
| 55 | P2RX7 | NA | 51834 | -0.189 | -0.1720 | Yes |
| 56 | TCIRG1 | NA | 51868 | -0.189 | -0.1458 | Yes |
| 57 | ATP6AP1 | NA | 52741 | -0.205 | -0.1329 | Yes |
| 58 | RAB3D | NA | 53154 | -0.215 | -0.1102 | Yes |
| 59 | ZNF675 | NA | 53258 | -0.217 | -0.0815 | Yes |
| 60 | PTH1R | NA | 53875 | -0.237 | -0.0593 | Yes |
| 61 | TRAF6 | NA | 54049 | -0.246 | -0.0278 | Yes |
| 62 | TMEM119 | NA | 54348 | -0.267 | 0.0045 | Yes |
