Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Adipose-Tissue.Adipose-Tissue.cls #Adipose-Tissue_20-29_versus_Adipose-Tissue_30-39.Adipose-Tissue.cls #Adipose-Tissue_20-29_versus_Adipose-Tissue_30-39_repos |
| Phenotype | Adipose-Tissue.cls#Adipose-Tissue_20-29_versus_Adipose-Tissue_30-39_repos |
| Upregulated in class | Adipose-Tissue_30-39 |
| GeneSet | GOBP_CYCLIC_NUCLEOTIDE_METABOLIC_PROCESS |
| Enrichment Score (ES) | -0.5393965 |
| Normalized Enrichment Score (NES) | -1.6017239 |
| Nominal p-value | 0.017928287 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.889 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | ADCY3 | NA | 610 | 0.199 | 0.0345 | No |
| 2 | ADCY8 | NA | 3265 | 0.105 | 0.0100 | No |
| 3 | NPR1 | NA | 3716 | 0.098 | 0.0243 | No |
| 4 | ADCY5 | NA | 4009 | 0.094 | 0.0405 | No |
| 5 | NPPC | NA | 4234 | 0.091 | 0.0572 | No |
| 6 | PDE8B | NA | 7224 | 0.059 | 0.0158 | No |
| 7 | PDE8A | NA | 9950 | 0.037 | -0.0256 | No |
| 8 | NPPA | NA | 10510 | 0.033 | -0.0281 | No |
| 9 | NPPB | NA | 11039 | 0.030 | -0.0309 | No |
| 10 | PDE10A | NA | 13398 | 0.017 | -0.0703 | No |
| 11 | AMPD2 | NA | 14258 | 0.013 | -0.0831 | No |
| 12 | CNP | NA | 14456 | 0.012 | -0.0840 | No |
| 13 | ADCY10 | NA | 24513 | -0.011 | -0.2658 | No |
| 14 | EPHA2 | NA | 25153 | -0.013 | -0.2744 | No |
| 15 | PDE4D | NA | 26442 | -0.019 | -0.2938 | No |
| 16 | PTHLH | NA | 27299 | -0.023 | -0.3043 | No |
| 17 | ADCY6 | NA | 32317 | -0.046 | -0.3856 | No |
| 18 | ADCY2 | NA | 33694 | -0.053 | -0.3987 | No |
| 19 | PDE4B | NA | 38334 | -0.078 | -0.4658 | No |
| 20 | PTH | NA | 40626 | -0.092 | -0.4867 | No |
| 21 | PDE2A | NA | 43503 | -0.110 | -0.5141 | Yes |
| 22 | GUCY1A2 | NA | 44269 | -0.116 | -0.5015 | Yes |
| 23 | PDE4A | NA | 46060 | -0.129 | -0.5047 | Yes |
| 24 | GUCY2F | NA | 46235 | -0.131 | -0.4779 | Yes |
| 25 | ADCY7 | NA | 46472 | -0.132 | -0.4518 | Yes |
| 26 | GUCY2C | NA | 46659 | -0.134 | -0.4244 | Yes |
| 27 | PDE7B | NA | 48379 | -0.149 | -0.4217 | Yes |
| 28 | PDE9A | NA | 48752 | -0.152 | -0.3935 | Yes |
| 29 | PDE1A | NA | 49503 | -0.160 | -0.3705 | Yes |
| 30 | PDE5A | NA | 50396 | -0.169 | -0.3480 | Yes |
| 31 | ADCY9 | NA | 51569 | -0.185 | -0.3270 | Yes |
| 32 | ADCY4 | NA | 52350 | -0.197 | -0.2960 | Yes |
| 33 | RORA | NA | 53327 | -0.219 | -0.2636 | Yes |
| 34 | NPR2 | NA | 53621 | -0.228 | -0.2165 | Yes |
| 35 | PDE4C | NA | 53981 | -0.242 | -0.1675 | Yes |
| 36 | ADCY1 | NA | 54122 | -0.250 | -0.1127 | Yes |
| 37 | GUCY2D | NA | 54265 | -0.259 | -0.0558 | Yes |
| 38 | PDE7A | NA | 54362 | -0.269 | 0.0042 | Yes |
