Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Adipose-Tissue.Adipose-Tissue.cls #Adipose-Tissue_20-29_versus_Adipose-Tissue_30-39.Adipose-Tissue.cls #Adipose-Tissue_20-29_versus_Adipose-Tissue_30-39_repos |
| Phenotype | Adipose-Tissue.cls#Adipose-Tissue_20-29_versus_Adipose-Tissue_30-39_repos |
| Upregulated in class | Adipose-Tissue_30-39 |
| GeneSet | GOBP_NEGATIVE_REGULATION_OF_ENDOCYTOSIS |
| Enrichment Score (ES) | -0.55978775 |
| Normalized Enrichment Score (NES) | -1.6104056 |
| Nominal p-value | 0.0057803467 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.88 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | ADIPOQ | NA | 678 | 0.194 | 0.0238 | No |
| 2 | ITGB3 | NA | 3666 | 0.099 | -0.0125 | No |
| 3 | SH3GL3 | NA | 7282 | 0.058 | -0.0679 | No |
| 4 | SDCBP | NA | 8567 | 0.047 | -0.0826 | No |
| 5 | MIR27B | NA | 9807 | 0.038 | -0.0981 | No |
| 6 | LGALS3 | NA | 10896 | 0.031 | -0.1123 | No |
| 7 | MIR205 | NA | 12251 | 0.023 | -0.1328 | No |
| 8 | ANKRD13B | NA | 12261 | 0.023 | -0.1287 | No |
| 9 | APOC1 | NA | 13857 | 0.015 | -0.1553 | No |
| 10 | NECAB2 | NA | 15039 | 0.009 | -0.1752 | No |
| 11 | ARF6 | NA | 17365 | 0.000 | -0.2178 | No |
| 12 | MIR185 | NA | 20187 | 0.000 | -0.2695 | No |
| 13 | PICALM | NA | 23093 | -0.006 | -0.3217 | No |
| 14 | PACSIN3 | NA | 23321 | -0.006 | -0.3247 | No |
| 15 | ITGAV | NA | 24956 | -0.013 | -0.3523 | No |
| 16 | PCSK9 | NA | 25075 | -0.013 | -0.3520 | No |
| 17 | LRPAP1 | NA | 25885 | -0.016 | -0.3638 | No |
| 18 | MIR199A1 | NA | 26367 | -0.018 | -0.3692 | No |
| 19 | ABCA2 | NA | 27665 | -0.024 | -0.3884 | No |
| 20 | MCTP1 | NA | 30753 | -0.038 | -0.4378 | No |
| 21 | PACSIN1 | NA | 31440 | -0.042 | -0.4426 | No |
| 22 | APOC3 | NA | 37073 | -0.071 | -0.5325 | No |
| 23 | MIR27A | NA | 37410 | -0.073 | -0.5250 | No |
| 24 | ABCA7 | NA | 38598 | -0.080 | -0.5318 | No |
| 25 | ATXN2 | NA | 40124 | -0.089 | -0.5432 | Yes |
| 26 | MTMR2 | NA | 40842 | -0.093 | -0.5389 | Yes |
| 27 | DLG4 | NA | 41230 | -0.095 | -0.5282 | Yes |
| 28 | NR1H2 | NA | 42460 | -0.103 | -0.5314 | Yes |
| 29 | PRKD1 | NA | 43304 | -0.109 | -0.5264 | Yes |
| 30 | CD300A | NA | 43361 | -0.109 | -0.5070 | Yes |
| 31 | LILRB1 | NA | 43720 | -0.112 | -0.4926 | Yes |
| 32 | NEU3 | NA | 44117 | -0.115 | -0.4784 | Yes |
| 33 | UBQLN2 | NA | 44733 | -0.119 | -0.4674 | Yes |
| 34 | CAV1 | NA | 45471 | -0.125 | -0.4576 | Yes |
| 35 | APOC2 | NA | 45732 | -0.127 | -0.4386 | Yes |
| 36 | NR1H3 | NA | 45917 | -0.128 | -0.4180 | Yes |
| 37 | RUBCN | NA | 46169 | -0.130 | -0.3983 | Yes |
| 38 | WDR54 | NA | 47032 | -0.137 | -0.3884 | Yes |
| 39 | RAC1 | NA | 47753 | -0.144 | -0.3747 | Yes |
| 40 | UNC119 | NA | 47983 | -0.146 | -0.3516 | Yes |
| 41 | PROM2 | NA | 48422 | -0.150 | -0.3316 | Yes |
| 42 | SNX33 | NA | 49903 | -0.164 | -0.3281 | Yes |
| 43 | RIN3 | NA | 50360 | -0.169 | -0.3048 | Yes |
| 44 | LRRTM2 | NA | 52732 | -0.205 | -0.3099 | Yes |
| 45 | PACSIN2 | NA | 52863 | -0.208 | -0.2734 | Yes |
| 46 | LRSAM1 | NA | 52896 | -0.208 | -0.2350 | Yes |
| 47 | STX1B | NA | 52906 | -0.209 | -0.1962 | Yes |
| 48 | ANKRD13D | NA | 53185 | -0.215 | -0.1610 | Yes |
| 49 | ANKRD13A | NA | 53206 | -0.216 | -0.1210 | Yes |
| 50 | SYT11 | NA | 54027 | -0.245 | -0.0902 | Yes |
| 51 | EPHA3 | NA | 54298 | -0.262 | -0.0460 | Yes |
| 52 | SCAMP5 | NA | 54404 | -0.274 | 0.0034 | Yes |
