| Dataset | Adipose-Tissue.Adipose-Tissue.cls #Adipose-Tissue_20-29_versus_Adipose-Tissue_30-39.Adipose-Tissue.cls #Adipose-Tissue_20-29_versus_Adipose-Tissue_30-39_repos |
| Phenotype | Adipose-Tissue.cls#Adipose-Tissue_20-29_versus_Adipose-Tissue_30-39_repos |
| Upregulated in class | Adipose-Tissue_30-39 |
| GeneSet | GOBP_REGULATION_OF_LEUKOCYTE_PROLIFERATION |
| Enrichment Score (ES) | -0.4769759 |
| Normalized Enrichment Score (NES) | -1.5273228 |
| Nominal p-value | 0.053537283 |
| FDR q-value | 0.85046244 |
| FWER p-Value | 0.948 |

| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | IGF1 | NA | 1 | 0.430 | 0.0171 | No |
| 2 | SLC7A1 | NA | 241 | 0.246 | 0.0224 | No |
| 3 | DNAJA3 | NA | 411 | 0.219 | 0.0280 | No |
| 4 | FADD | NA | 496 | 0.210 | 0.0348 | No |
| 5 | SDC4 | NA | 727 | 0.190 | 0.0381 | No |
| 6 | EFNB1 | NA | 825 | 0.183 | 0.0436 | No |
| 7 | ARG2 | NA | 2185 | 0.126 | 0.0236 | No |
| 8 | CEBPB | NA | 2335 | 0.123 | 0.0257 | No |
| 9 | PNP | NA | 2395 | 0.121 | 0.0294 | No |
| 10 | CLCF1 | NA | 2453 | 0.120 | 0.0332 | No |
| 11 | CHRNB2 | NA | 3116 | 0.108 | 0.0253 | No |
| 12 | CLC | NA | 3804 | 0.097 | 0.0165 | No |
| 13 | VCAM1 | NA | 3876 | 0.096 | 0.0190 | No |
| 14 | CCL8 | NA | 3897 | 0.095 | 0.0224 | No |
| 15 | CD81 | NA | 4048 | 0.093 | 0.0233 | No |
| 16 | TFRC | NA | 4336 | 0.089 | 0.0216 | No |
| 17 | TNFRSF21 | NA | 4546 | 0.087 | 0.0212 | No |
| 18 | CLEC4G | NA | 5670 | 0.073 | 0.0034 | No |
| 19 | GREM1 | NA | 5681 | 0.073 | 0.0061 | No |
| 20 | IL12A | NA | 5958 | 0.070 | 0.0038 | No |
| 21 | IL6 | NA | 5959 | 0.070 | 0.0066 | No |
| 22 | PRKAR1A | NA | 6595 | 0.064 | -0.0025 | No |
| 23 | ZBTB7B | NA | 6681 | 0.063 | -0.0016 | No |
| 24 | IRS2 | NA | 6918 | 0.061 | -0.0035 | No |
| 25 | CD55 | NA | 7037 | 0.060 | -0.0033 | No |
| 26 | VTCN1 | NA | 7122 | 0.059 | -0.0025 | No |
| 27 | MIR21 | NA | 7297 | 0.058 | -0.0034 | No |
| 28 | IL13 | NA | 7397 | 0.057 | -0.0029 | No |
| 29 | MIR181C | NA | 7938 | 0.052 | -0.0108 | No |
| 30 | IL1A | NA | 9256 | 0.042 | -0.0333 | No |
| 31 | TNFRSF4 | NA | 9277 | 0.042 | -0.0320 | No |
| 32 | GPAM | NA | 9499 | 0.040 | -0.0345 | No |
| 33 | CSF1 | NA | 9541 | 0.040 | -0.0337 | No |
| 34 | ANXA1 | NA | 9769 | 0.039 | -0.0363 | No |
| 35 | CD209 | NA | 10487 | 0.034 | -0.0482 | No |
| 36 | FOXJ1 | NA | 10542 | 0.033 | -0.0479 | No |
| 37 | IL23A | NA | 10803 | 0.032 | -0.0514 | No |
| 38 | GAL | NA | 10888 | 0.031 | -0.0517 | No |
| 39 | LGALS3 | NA | 10896 | 0.031 | -0.0506 | No |
| 40 | NFATC2 | NA | 11079 | 0.030 | -0.0528 | No |
| 41 | WNT3A | NA | 11663 | 0.026 | -0.0624 | No |
| 42 | ARG1 | NA | 12016 | 0.024 | -0.0680 | No |
| 43 | CDKN1A | NA | 12069 | 0.024 | -0.0680 | No |
| 44 | FGF10 | NA | 13153 | 0.018 | -0.0872 | No |
| 45 | IGFBP2 | NA | 13220 | 0.018 | -0.0877 | No |
| 46 | MIR30B | NA | 13406 | 0.017 | -0.0904 | No |
| 47 | TNFAIP3 | NA | 13568 | 0.016 | -0.0928 | No |
| 48 | RPS3 | NA | 14043 | 0.014 | -0.1009 | No |
| 49 | GLMN | NA | 14250 | 0.013 | -0.1042 | No |
| 50 | JAK3 | NA | 14342 | 0.012 | -0.1054 | No |
| 51 | CD274 | NA | 14465 | 0.012 | -0.1072 | No |
| 52 | MAPK8IP1 | NA | 14819 | 0.010 | -0.1133 | No |
| 53 | VAV3 | NA | 15292 | 0.008 | -0.1216 | No |
| 54 | SFTPD | NA | 16104 | 0.005 | -0.1363 | No |
| 55 | CR1 | NA | 16145 | 0.005 | -0.1369 | No |
| 56 | IRF1 | NA | 16340 | 0.004 | -0.1403 | No |
| 57 | PRNP | NA | 16604 | 0.003 | -0.1450 | No |
| 58 | ZP4 | NA | 17218 | 0.001 | -0.1562 | No |
| 59 | MIR181B1 | NA | 21888 | -0.002 | -0.2421 | No |
| 60 | CD320 | NA | 22024 | -0.003 | -0.2444 | No |
| 61 | TAC1 | NA | 22099 | -0.003 | -0.2457 | No |
| 62 | IL12B | NA | 22462 | -0.004 | -0.2522 | No |
| 63 | BCL2 | NA | 23983 | -0.009 | -0.2798 | No |
| 64 | IL2RA | NA | 24430 | -0.011 | -0.2876 | No |
| 65 | IL1B | NA | 24779 | -0.012 | -0.2935 | No |
| 66 | SCRIB | NA | 26515 | -0.019 | -0.3247 | No |
| 67 | CCR2 | NA | 26543 | -0.019 | -0.3244 | No |
| 68 | CD24 | NA | 26688 | -0.020 | -0.3263 | No |
| 69 | PLA2G2F | NA | 26905 | -0.021 | -0.3295 | No |
| 70 | VSIG4 | NA | 27412 | -0.023 | -0.3378 | No |
| 71 | LILRB2 | NA | 27661 | -0.024 | -0.3415 | No |
| 72 | MAD1L1 | NA | 27731 | -0.024 | -0.3418 | No |
| 73 | MIF | NA | 27828 | -0.025 | -0.3425 | No |
| 74 | IL10 | NA | 28087 | -0.026 | -0.3463 | No |
| 75 | CD1D | NA | 28438 | -0.028 | -0.3516 | No |
| 76 | IHH | NA | 28575 | -0.028 | -0.3530 | No |
| 77 | CRP | NA | 29121 | -0.031 | -0.3618 | No |
| 78 | MNDA | NA | 29446 | -0.033 | -0.3664 | No |
| 79 | SPTA1 | NA | 30281 | -0.036 | -0.3803 | No |
| 80 | DLG5 | NA | 30482 | -0.037 | -0.3826 | No |
| 81 | GSTP1 | NA | 30772 | -0.039 | -0.3863 | No |
| 82 | TICAM1 | NA | 30801 | -0.039 | -0.3853 | No |
| 83 | TNFRSF1B | NA | 30859 | -0.039 | -0.3848 | No |
| 84 | IL33 | NA | 31161 | -0.040 | -0.3888 | No |
| 85 | CORO1A | NA | 31248 | -0.041 | -0.3887 | No |
| 86 | CD38 | NA | 31999 | -0.045 | -0.4008 | No |
| 87 | IL4 | NA | 32256 | -0.046 | -0.4036 | No |
| 88 | MYD88 | NA | 32390 | -0.046 | -0.4042 | No |
| 89 | SCGB1A1 | NA | 33416 | -0.052 | -0.4211 | No |
| 90 | ICOSLG | NA | 33454 | -0.052 | -0.4197 | No |
| 91 | BLK | NA | 33814 | -0.054 | -0.4242 | No |
| 92 | LST1 | NA | 33923 | -0.054 | -0.4240 | No |
| 93 | TNFSF18 | NA | 33948 | -0.054 | -0.4223 | No |
| 94 | SOX11 | NA | 33982 | -0.055 | -0.4207 | No |
| 95 | IL23R | NA | 34139 | -0.055 | -0.4214 | No |
| 96 | SLC39A10 | NA | 35189 | -0.061 | -0.4382 | No |
| 97 | SELENOK | NA | 35407 | -0.062 | -0.4398 | No |
| 98 | LGALS7B | NA | 36105 | -0.066 | -0.4500 | No |
| 99 | MAPK1 | NA | 36285 | -0.067 | -0.4506 | No |
| 100 | TLR4 | NA | 36502 | -0.068 | -0.4519 | No |
| 101 | RIPK2 | NA | 36568 | -0.069 | -0.4503 | No |
| 102 | IL27RA | NA | 36653 | -0.069 | -0.4492 | No |
| 103 | SH3RF1 | NA | 36800 | -0.070 | -0.4491 | No |
| 104 | CD276 | NA | 36845 | -0.070 | -0.4471 | No |
| 105 | MZB1 | NA | 37188 | -0.072 | -0.4505 | No |
| 106 | CCL19 | NA | 37597 | -0.074 | -0.4551 | No |
| 107 | VSIR | NA | 37952 | -0.076 | -0.4586 | No |
| 108 | FOXP3 | NA | 38039 | -0.077 | -0.4571 | No |
| 109 | LEP | NA | 38312 | -0.078 | -0.4591 | No |
| 110 | IL21 | NA | 38317 | -0.078 | -0.4560 | No |
| 111 | LYN | NA | 38497 | -0.079 | -0.4562 | No |
| 112 | LRRC32 | NA | 38856 | -0.081 | -0.4595 | No |
| 113 | HAVCR2 | NA | 39654 | -0.086 | -0.4708 | No |
| 114 | TNFRSF13B | NA | 39991 | -0.088 | -0.4735 | Yes |
| 115 | CD86 | NA | 40086 | -0.089 | -0.4717 | Yes |
| 116 | IL5 | NA | 40275 | -0.090 | -0.4716 | Yes |
| 117 | PLA2G2D | NA | 40425 | -0.091 | -0.4707 | Yes |
| 118 | ZNF335 | NA | 40541 | -0.091 | -0.4692 | Yes |
| 119 | IL6ST | NA | 40622 | -0.092 | -0.4671 | Yes |
| 120 | PTH | NA | 40626 | -0.092 | -0.4635 | Yes |
| 121 | STAT5B | NA | 40860 | -0.093 | -0.4641 | Yes |
| 122 | TMIGD2 | NA | 40975 | -0.094 | -0.4624 | Yes |
| 123 | HHLA2 | NA | 41411 | -0.097 | -0.4666 | Yes |
| 124 | EPO | NA | 41499 | -0.097 | -0.4644 | Yes |
| 125 | CTLA4 | NA | 41796 | -0.099 | -0.4659 | Yes |
| 126 | IL7 | NA | 41974 | -0.100 | -0.4652 | Yes |
| 127 | CLECL1 | NA | 42079 | -0.101 | -0.4631 | Yes |
| 128 | IL27 | NA | 42301 | -0.102 | -0.4631 | Yes |
| 129 | TIRAP | NA | 42563 | -0.104 | -0.4637 | Yes |
| 130 | ZP3 | NA | 42702 | -0.105 | -0.4621 | Yes |
| 131 | CD300A | NA | 43361 | -0.109 | -0.4699 | Yes |
| 132 | SHH | NA | 43384 | -0.109 | -0.4660 | Yes |
| 133 | SOS1 | NA | 43497 | -0.110 | -0.4636 | Yes |
| 134 | IL20RB | NA | 43628 | -0.111 | -0.4616 | Yes |
| 135 | LILRB1 | NA | 43720 | -0.112 | -0.4589 | Yes |
| 136 | TNFSF8 | NA | 43733 | -0.112 | -0.4546 | Yes |
| 137 | CBLB | NA | 43798 | -0.112 | -0.4514 | Yes |
| 138 | PTPRC | NA | 44039 | -0.114 | -0.4512 | Yes |
| 139 | PAWR | NA | 44565 | -0.118 | -0.4562 | Yes |
| 140 | CCL5 | NA | 44604 | -0.118 | -0.4522 | Yes |
| 141 | NCK1 | NA | 44626 | -0.118 | -0.4479 | Yes |
| 142 | SASH3 | NA | 44692 | -0.119 | -0.4444 | Yes |
| 143 | TNFSF4 | NA | 44738 | -0.119 | -0.4405 | Yes |
| 144 | BCL6 | NA | 44780 | -0.119 | -0.4365 | Yes |
| 145 | TGFBR2 | NA | 44890 | -0.120 | -0.4337 | Yes |
| 146 | AGER | NA | 44895 | -0.120 | -0.4290 | Yes |
| 147 | HHEX | NA | 45034 | -0.121 | -0.4267 | Yes |
| 148 | AHR | NA | 45042 | -0.121 | -0.4221 | Yes |
| 149 | LILRB4 | NA | 45096 | -0.122 | -0.4182 | Yes |
| 150 | CD70 | NA | 45098 | -0.122 | -0.4134 | Yes |
| 151 | INPP5D | NA | 45188 | -0.123 | -0.4102 | Yes |
| 152 | FCRL3 | NA | 45456 | -0.125 | -0.4101 | Yes |
| 153 | CD6 | NA | 45632 | -0.126 | -0.4083 | Yes |
| 154 | CD4 | NA | 45788 | -0.127 | -0.4062 | Yes |
| 155 | CD28 | NA | 45825 | -0.127 | -0.4018 | Yes |
| 156 | GPR183 | NA | 45898 | -0.128 | -0.3980 | Yes |
| 157 | IGF2 | NA | 46221 | -0.130 | -0.3988 | Yes |
| 158 | CSF1R | NA | 46225 | -0.130 | -0.3936 | Yes |
| 159 | AIF1 | NA | 46237 | -0.131 | -0.3887 | Yes |
| 160 | LGALS9 | NA | 46274 | -0.131 | -0.3841 | Yes |
| 161 | TYROBP | NA | 46299 | -0.131 | -0.3794 | Yes |
| 162 | CD3E | NA | 46377 | -0.132 | -0.3756 | Yes |
| 163 | LGALS9C | NA | 46387 | -0.132 | -0.3705 | Yes |
| 164 | IKZF3 | NA | 46521 | -0.133 | -0.3677 | Yes |
| 165 | IL12RB1 | NA | 46615 | -0.134 | -0.3641 | Yes |
| 166 | TNFRSF13C | NA | 46623 | -0.134 | -0.3589 | Yes |
| 167 | ADA | NA | 46625 | -0.134 | -0.3536 | Yes |
| 168 | FCGR2B | NA | 46685 | -0.134 | -0.3493 | Yes |
| 169 | MEF2C | NA | 46701 | -0.135 | -0.3443 | Yes |
| 170 | TNFSF13B | NA | 46865 | -0.136 | -0.3419 | Yes |
| 171 | CD40 | NA | 46868 | -0.136 | -0.3365 | Yes |
| 172 | IL18 | NA | 47019 | -0.137 | -0.3338 | Yes |
| 173 | BST1 | NA | 47114 | -0.138 | -0.3301 | Yes |
| 174 | ENPP3 | NA | 47460 | -0.141 | -0.3308 | Yes |
| 175 | OCSTAMP | NA | 47549 | -0.142 | -0.3268 | Yes |
| 176 | PKN1 | NA | 47550 | -0.142 | -0.3212 | Yes |
| 177 | RASAL3 | NA | 47558 | -0.142 | -0.3157 | Yes |
| 178 | TNFSF9 | NA | 47748 | -0.143 | -0.3135 | Yes |
| 179 | MPL | NA | 47754 | -0.144 | -0.3079 | Yes |
| 180 | DLG1 | NA | 47814 | -0.144 | -0.3032 | Yes |
| 181 | PELI1 | NA | 48034 | -0.146 | -0.3014 | Yes |
| 182 | TWSG1 | NA | 48158 | -0.147 | -0.2979 | Yes |
| 183 | EBI3 | NA | 48264 | -0.148 | -0.2939 | Yes |
| 184 | NCK2 | NA | 48356 | -0.149 | -0.2897 | Yes |
| 185 | BMP4 | NA | 48475 | -0.150 | -0.2859 | Yes |
| 186 | PTPN22 | NA | 48559 | -0.151 | -0.2814 | Yes |
| 187 | IDO1 | NA | 48642 | -0.151 | -0.2769 | Yes |
| 188 | IL34 | NA | 48726 | -0.152 | -0.2724 | Yes |
| 189 | NCKAP1L | NA | 48786 | -0.153 | -0.2675 | Yes |
| 190 | CD80 | NA | 48902 | -0.154 | -0.2635 | Yes |
| 191 | SYK | NA | 48916 | -0.154 | -0.2576 | Yes |
| 192 | BST2 | NA | 48952 | -0.154 | -0.2521 | Yes |
| 193 | CD46 | NA | 48953 | -0.154 | -0.2460 | Yes |
| 194 | IL15 | NA | 48982 | -0.155 | -0.2404 | Yes |
| 195 | TLR9 | NA | 49165 | -0.156 | -0.2375 | Yes |
| 196 | SOS2 | NA | 49248 | -0.157 | -0.2328 | Yes |
| 197 | IL5RA | NA | 49252 | -0.157 | -0.2266 | Yes |
| 198 | HLA-A | NA | 49322 | -0.158 | -0.2216 | Yes |
| 199 | PTPN6 | NA | 49341 | -0.158 | -0.2156 | Yes |
| 200 | KITLG | NA | 49494 | -0.160 | -0.2121 | Yes |
| 201 | RAC2 | NA | 49553 | -0.160 | -0.2068 | Yes |
| 202 | PTK2 | NA | 49737 | -0.162 | -0.2037 | Yes |
| 203 | HMGB1 | NA | 49773 | -0.163 | -0.1979 | Yes |
| 204 | NDFIP1 | NA | 49911 | -0.164 | -0.1939 | Yes |
| 205 | HLA-G | NA | 49970 | -0.165 | -0.1884 | Yes |
| 206 | MAPK3 | NA | 50042 | -0.166 | -0.1832 | Yes |
| 207 | GNRH1 | NA | 50112 | -0.166 | -0.1778 | Yes |
| 208 | PDCD1LG2 | NA | 50124 | -0.166 | -0.1714 | Yes |
| 209 | CRTAM | NA | 50250 | -0.168 | -0.1671 | Yes |
| 210 | ERBB2 | NA | 50458 | -0.170 | -0.1641 | Yes |
| 211 | HES1 | NA | 50785 | -0.174 | -0.1632 | Yes |
| 212 | SPN | NA | 50985 | -0.177 | -0.1598 | Yes |
| 213 | XCL1 | NA | 51042 | -0.178 | -0.1538 | Yes |
| 214 | HLA-DPB1 | NA | 51197 | -0.180 | -0.1495 | Yes |
| 215 | RIPK3 | NA | 51224 | -0.180 | -0.1429 | Yes |
| 216 | LMO1 | NA | 51481 | -0.184 | -0.1403 | Yes |
| 217 | ZAP70 | NA | 51495 | -0.184 | -0.1332 | Yes |
| 218 | CD40LG | NA | 51526 | -0.184 | -0.1264 | Yes |
| 219 | LGALS9B | NA | 51562 | -0.185 | -0.1198 | Yes |
| 220 | CD22 | NA | 51670 | -0.186 | -0.1143 | Yes |
| 221 | PYCARD | NA | 51821 | -0.189 | -0.1096 | Yes |
| 222 | CARD11 | NA | 51850 | -0.189 | -0.1026 | Yes |
| 223 | IL2 | NA | 52024 | -0.192 | -0.0982 | Yes |
| 224 | GPNMB | NA | 52324 | -0.197 | -0.0959 | Yes |
| 225 | CASP3 | NA | 52484 | -0.200 | -0.0909 | Yes |
| 226 | BTK | NA | 52490 | -0.200 | -0.0830 | Yes |
| 227 | RC3H1 | NA | 52555 | -0.201 | -0.0762 | Yes |
| 228 | HLA-DRB1 | NA | 52708 | -0.204 | -0.0709 | Yes |
| 229 | CD74 | NA | 53150 | -0.214 | -0.0705 | Yes |
| 230 | CCDC88B | NA | 53234 | -0.217 | -0.0634 | Yes |
| 231 | FLT3LG | NA | 53292 | -0.218 | -0.0558 | Yes |
| 232 | ATM | NA | 53616 | -0.228 | -0.0527 | Yes |
| 233 | HLA-DPA1 | NA | 53623 | -0.228 | -0.0437 | Yes |
| 234 | PRKCQ | NA | 53674 | -0.231 | -0.0355 | Yes |
| 235 | HLA-E | NA | 53772 | -0.234 | -0.0280 | Yes |
| 236 | TRAF6 | NA | 54049 | -0.246 | -0.0233 | Yes |
| 237 | HLA-DMB | NA | 54148 | -0.251 | -0.0152 | Yes |
| 238 | BTN2A2 | NA | 54185 | -0.253 | -0.0058 | Yes |
| 239 | TNFRSF14 | NA | 54580 | -0.333 | 0.0002 | Yes |

