Details for gene set GOBP_INSULIN_RECEPTOR_SIGNALING

Table: GSEA Results Summary

Dataset	Breast.Breast.cls #Breast_30-39_versus_Breast_70-79.Breast.cls #Breast_30-39_versus_Breast_70-79_repos
Phenotype	Breast.cls#Breast_30-39_versus_Breast_70-79_repos
Upregulated in class	Breast_30-39
GeneSet	GOBP_INSULIN_RECEPTOR_SIGNALING_PATHWAY
Enrichment Score (ES)	0.5469589
Normalized Enrichment Score (NES)	1.6732457
Nominal p-value	0.0051993066
FDR q-value	0.27238572
FWER p-Value	0.744

Table: GSEA details [plain text format]
	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	ZNF106	NA	78	0.743	0.0195	Yes
2	PIP4K2B	NA	221	0.663	0.0356	Yes
3	MSTN	NA	238	0.657	0.0539	Yes
4	GSK3B	NA	325	0.632	0.0701	Yes
5	FOXO4	NA	359	0.623	0.0871	Yes
6	ZBTB7B	NA	421	0.610	0.1031	Yes
7	ATP6V1E2	NA	454	0.603	0.1196	Yes
8	APC	NA	645	0.570	0.1322	Yes
9	KANK1	NA	740	0.558	0.1462	Yes
10	ATP6V1A	NA	932	0.536	0.1578	Yes
11	INPP5K	NA	1017	0.528	0.1711	Yes
12	PTPN11	NA	1141	0.517	0.1835	Yes
13	TSC2	NA	1147	0.516	0.1979	Yes
14	OPA1	NA	1153	0.516	0.2124	Yes
15	C2CD5	NA	1305	0.503	0.2238	Yes
16	AKT2	NA	1358	0.498	0.2369	Yes
17	GRB10	NA	1373	0.497	0.2507	Yes
18	AKT1	NA	1390	0.496	0.2644	Yes
19	LEP	NA	1684	0.477	0.2725	Yes
20	PRKCD	NA	1888	0.463	0.2818	Yes
21	PDK2	NA	2412	0.435	0.2845	Yes
22	GRB2	NA	2497	0.431	0.2951	Yes
23	TSC1	NA	2614	0.426	0.3050	Yes
24	PIK3CA	NA	2652	0.424	0.3163	Yes
25	SIRT1	NA	2723	0.421	0.3269	Yes
26	PIK3R1	NA	2739	0.420	0.3385	Yes
27	SOS1	NA	2754	0.420	0.3500	Yes
28	SLC27A4	NA	3199	0.402	0.3532	Yes
29	RPS6KB1	NA	3228	0.401	0.3640	Yes
30	OGT	NA	3581	0.388	0.3685	Yes
31	NCOA5	NA	3699	0.384	0.3772	Yes
32	SNX5	NA	3720	0.383	0.3876	Yes
33	SOGA1	NA	3947	0.375	0.3941	Yes
34	IDE	NA	3980	0.375	0.4041	Yes
35	FER	NA	4254	0.367	0.4094	Yes
36	EIF4EBP2	NA	4590	0.357	0.4133	Yes
37	ENPP1	NA	4763	0.352	0.4201	Yes
38	PIK3R2	NA	5143	0.342	0.4227	Yes
39	ATP6V0E2	NA	5146	0.342	0.4323	Yes
40	ATP6V0A4	NA	5361	0.335	0.4379	Yes
41	INS	NA	5395	0.335	0.4467	Yes
42	SORL1	NA	5570	0.331	0.4528	Yes
43	SORBS1	NA	5768	0.326	0.4584	Yes
44	STXBP4	NA	5781	0.326	0.4674	Yes
45	SMARCC1	NA	6037	0.320	0.4717	Yes
46	IGF1R	NA	6119	0.318	0.4792	Yes
47	ATP6V0A2	NA	6379	0.312	0.4833	Yes
48	ATP6AP1	NA	6657	0.306	0.4868	Yes
49	IRS1	NA	6700	0.305	0.4946	Yes
50	ATP6V1C1	NA	6933	0.300	0.4988	Yes
51	IRS2	NA	7052	0.298	0.5051	Yes
52	FOXO1	NA	7408	0.291	0.5068	Yes
53	PHIP	NA	7842	0.282	0.5068	Yes
54	PIK3C2A	NA	8112	0.277	0.5096	Yes
55	APPL1	NA	8192	0.275	0.5159	Yes
56	SRC	NA	8379	0.272	0.5202	Yes
57	ATP6V0D1	NA	8790	0.265	0.5202	Yes
58	PTPRA	NA	8928	0.263	0.5250	Yes
59	ATP6V0A1	NA	9309	0.256	0.5253	Yes
60	SESN3	NA	9310	0.256	0.5325	Yes
61	INSR	NA	9620	0.250	0.5339	Yes
62	IGFBP1	NA	9667	0.250	0.5401	Yes
63	PAK1	NA	9677	0.250	0.5470	Yes
64	ATP6V1G2	NA	10512	0.236	0.5383	No
65	GSK3A	NA	11015	0.229	0.5355	No
66	NUCKS1	NA	11303	0.224	0.5366	No
67	ATP6V1B2	NA	12000	0.215	0.5299	No
68	RHOQ	NA	12252	0.211	0.5312	No
69	IRS4	NA	12543	0.207	0.5317	No
70	PIP4K2C	NA	12621	0.206	0.5361	No
71	ATP6V1D	NA	13206	0.198	0.5310	No
72	PRKAA1	NA	13261	0.197	0.5356	No
73	SLC2A8	NA	13504	0.193	0.5366	No
74	OSBPL8	NA	13867	0.188	0.5352	No
75	TNS2	NA	14033	0.186	0.5375	No
76	SIK2	NA	14492	0.180	0.5341	No
77	ATP6V0E1	NA	14496	0.180	0.5392	No
78	ATP6V0D2	NA	14824	0.176	0.5381	No
79	RPE65	NA	15271	0.170	0.5348	No
80	MZB1	NA	15862	0.163	0.5285	No
81	ENHO	NA	16019	0.161	0.5302	No
82	BAIAP2L1	NA	16910	0.150	0.5181	No
83	CSRP3	NA	16911	0.150	0.5223	No
84	PRKCZ	NA	17376	0.145	0.5179	No
85	ATP6V1H	NA	17534	0.143	0.5190	No
86	PTPRE	NA	17645	0.141	0.5210	No
87	BCAR3	NA	17983	0.137	0.5187	No
88	SHC1	NA	18018	0.136	0.5219	No
89	NR1H4	NA	18353	0.132	0.5195	No
90	SREBF1	NA	18357	0.132	0.5231	No
91	GPLD1	NA	18598	0.129	0.5224	No
92	PDK4	NA	19710	0.115	0.5052	No
93	PIK3R3	NA	20047	0.111	0.5022	No
94	PIP4K2A	NA	21146	0.098	0.4848	No
95	AP3S1	NA	21213	0.097	0.4863	No
96	BAIAP2	NA	22286	0.085	0.4690	No
97	ATP6V1C2	NA	22798	0.079	0.4619	No
98	CCND3	NA	22874	0.079	0.4627	No
99	IL1B	NA	23517	0.072	0.4529	No
100	ADIPOR1	NA	23859	0.068	0.4486	No
101	ATP6V1B1	NA	24089	0.066	0.4462	No
102	PID1	NA	24739	0.060	0.4360	No
103	CAV2	NA	24851	0.059	0.4356	No
104	SERPINA12	NA	25564	0.052	0.4240	No
105	PTPN1	NA	25762	0.050	0.4218	No
106	GAB1	NA	26457	0.044	0.4103	No
107	SLC39A14	NA	27398	0.037	0.3941	No
108	GRB14	NA	27793	0.034	0.3878	No
109	MIR107	NA	28878	0.027	0.3686	No
110	AHSG	NA	29322	0.024	0.3612	No
111	ATP6V0B	NA	31179	0.014	0.3275	No
112	ATP6V1G3	NA	33297	0.006	0.2888	No
113	INSRR	NA	33795	0.003	0.2797	No
114	MIR103A1	NA	35279	0.000	0.2525	No
115	GPR21	NA	36158	0.000	0.2363	No
116	SOCS1	NA	39789	-0.009	0.1699	No
117	PRKCB	NA	40625	-0.019	0.1551	No
118	VWA2	NA	40654	-0.020	0.1552	No
119	IGF2	NA	40933	-0.023	0.1507	No
120	ERFE	NA	41455	-0.029	0.1420	No
121	GKAP1	NA	41733	-0.032	0.1378	No
122	KL	NA	41871	-0.034	0.1362	No
123	PTPN2	NA	42872	-0.047	0.1192	No
124	ATP6V1E1	NA	43444	-0.054	0.1102	No
125	CDK4	NA	43717	-0.058	0.1069	No
126	ATP6V1F	NA	44080	-0.063	0.1020	No
127	ATP6V0C	NA	44182	-0.065	0.1020	No
128	C1QTNF12	NA	44539	-0.070	0.0974	No
129	PRKCQ	NA	44633	-0.071	0.0977	No
130	TRIM72	NA	46278	-0.096	0.0702	No
131	RARRES2	NA	46763	-0.103	0.0642	No
132	TCIRG1	NA	46776	-0.104	0.0669	No
133	ATP6V1G1	NA	47483	-0.116	0.0572	No
134	FUT7	NA	48169	-0.129	0.0483	No
135	GNAI2	NA	49326	-0.151	0.0313	No
136	NDEL1	NA	49903	-0.164	0.0254	No
137	NCK1	NA	51252	-0.196	0.0061	No
138	RELA	NA	53267	-0.259	-0.0235	No
139	SH2B2	NA	53549	-0.278	-0.0209	No
140	FOXC2	NA	53809	-0.302	-0.0171	No
141	FFAR3	NA	53872	-0.308	-0.0095	No
142	BCAR1	NA	54204	-0.364	-0.0053	No
143	SOCS3	NA	54415	-0.440	0.0032	No