Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Breast.Breast.cls #Breast_30-39_versus_Breast_70-79.Breast.cls #Breast_30-39_versus_Breast_70-79_repos |
| Phenotype | Breast.cls#Breast_30-39_versus_Breast_70-79_repos |
| Upregulated in class | Breast_30-39 |
| GeneSet | GOBP_PROTEIN_LOCALIZATION_TO_LYSOSOME |
| Enrichment Score (ES) | 0.62235045 |
| Normalized Enrichment Score (NES) | 1.6499177 |
| Nominal p-value | 0.014842301 |
| FDR q-value | 0.24179657 |
| FWER p-Value | 0.803 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | ATP13A2 | NA | 188 | 0.681 | 0.0511 | Yes |
| 2 | AP3M1 | NA | 623 | 0.573 | 0.0890 | Yes |
| 3 | NCOA4 | NA | 773 | 0.553 | 0.1306 | Yes |
| 4 | SORT1 | NA | 1238 | 0.509 | 0.1628 | Yes |
| 5 | CACNG8 | NA | 1776 | 0.469 | 0.1905 | Yes |
| 6 | NAGPA | NA | 2030 | 0.454 | 0.2222 | Yes |
| 7 | ZFYVE16 | NA | 2596 | 0.427 | 0.2461 | Yes |
| 8 | GNPTAB | NA | 2681 | 0.423 | 0.2784 | Yes |
| 9 | SZT2 | NA | 2741 | 0.420 | 0.3110 | Yes |
| 10 | AP3D1 | NA | 2825 | 0.416 | 0.3428 | Yes |
| 11 | SNX16 | NA | 2839 | 0.416 | 0.3759 | Yes |
| 12 | KPTN | NA | 3051 | 0.407 | 0.4046 | Yes |
| 13 | SCARB2 | NA | 3276 | 0.399 | 0.4325 | Yes |
| 14 | SH3BP4 | NA | 3593 | 0.388 | 0.4577 | Yes |
| 15 | MFSD1 | NA | 4124 | 0.371 | 0.4777 | Yes |
| 16 | HGS | NA | 4170 | 0.369 | 0.5064 | Yes |
| 17 | VPS4A | NA | 4481 | 0.360 | 0.5295 | Yes |
| 18 | AP3B1 | NA | 4493 | 0.360 | 0.5581 | Yes |
| 19 | SORL1 | NA | 5570 | 0.331 | 0.5649 | Yes |
| 20 | ROCK2 | NA | 5719 | 0.327 | 0.5883 | Yes |
| 21 | GGA3 | NA | 5841 | 0.324 | 0.6121 | Yes |
| 22 | GCC2 | NA | 6886 | 0.301 | 0.6170 | Yes |
| 23 | M6PR | NA | 8553 | 0.269 | 0.6080 | Yes |
| 24 | C12orf66 | NA | 8979 | 0.262 | 0.6212 | Yes |
| 25 | CD81 | NA | 9987 | 0.245 | 0.6224 | Yes |
| 26 | GLMP | NA | 12448 | 0.209 | 0.5940 | No |
| 27 | RTN4 | NA | 12532 | 0.207 | 0.6090 | No |
| 28 | RNF128 | NA | 14986 | 0.174 | 0.5780 | No |
| 29 | AP4M1 | NA | 15375 | 0.169 | 0.5844 | No |
| 30 | LMBRD1 | NA | 15614 | 0.166 | 0.5934 | No |
| 31 | LAMP2 | NA | 17036 | 0.149 | 0.5792 | No |
| 32 | CLU | NA | 17160 | 0.147 | 0.5887 | No |
| 33 | NEDD4 | NA | 20989 | 0.100 | 0.5265 | No |
| 34 | CACNG4 | NA | 23131 | 0.076 | 0.4933 | No |
| 35 | RAB7A | NA | 30138 | 0.020 | 0.3665 | No |
| 36 | HSPA8 | NA | 39913 | -0.011 | 0.1881 | No |
| 37 | CACNG7 | NA | 43846 | -0.060 | 0.1208 | No |
| 38 | GPR137B | NA | 43967 | -0.062 | 0.1236 | No |
| 39 | CACNG2 | NA | 44804 | -0.073 | 0.1141 | No |
| 40 | CACNG5 | NA | 45981 | -0.091 | 0.0998 | No |
| 41 | LAPTM5 | NA | 46576 | -0.100 | 0.0970 | No |
| 42 | WASH3P | NA | 46600 | -0.101 | 0.1046 | No |
| 43 | LAMTOR5 | NA | 47078 | -0.109 | 0.1046 | No |
| 44 | LAMTOR4 | NA | 48977 | -0.144 | 0.0814 | No |
| 45 | CACNG3 | NA | 53420 | -0.269 | 0.0215 | No |
