Dataset | Breast.Breast.cls #Breast_30-39_versus_Breast_70-79.Breast.cls #Breast_30-39_versus_Breast_70-79_repos |
Phenotype | Breast.cls#Breast_30-39_versus_Breast_70-79_repos |
Upregulated in class | Breast_30-39 |
GeneSet | GOBP_VACUOLAR_TRANSPORT |
Enrichment Score (ES) | 0.62576205 |
Normalized Enrichment Score (NES) | 1.7411283 |
Nominal p-value | 0.005524862 |
FDR q-value | 0.5293706 |
FWER p-Value | 0.523 |
SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|
1 | ATP13A2 | NA | 188 | 0.681 | 0.0132 | Yes |
2 | VPS33A | NA | 335 | 0.629 | 0.0259 | Yes |
3 | VPS18 | NA | 571 | 0.582 | 0.0358 | Yes |
4 | AP3M1 | NA | 623 | 0.573 | 0.0489 | Yes |
5 | NCOA4 | NA | 773 | 0.553 | 0.0597 | Yes |
6 | VPS13D | NA | 831 | 0.548 | 0.0721 | Yes |
7 | MON1B | NA | 898 | 0.542 | 0.0841 | Yes |
8 | VPS36 | NA | 937 | 0.536 | 0.0965 | Yes |
9 | KIF13A | NA | 942 | 0.536 | 0.1096 | Yes |
10 | TGFBRAP1 | NA | 976 | 0.532 | 0.1220 | Yes |
11 | ALS2 | NA | 1136 | 0.518 | 0.1317 | Yes |
12 | SORT1 | NA | 1238 | 0.509 | 0.1423 | Yes |
13 | TRAK1 | NA | 1465 | 0.491 | 0.1502 | Yes |
14 | AP1G1 | NA | 1483 | 0.489 | 0.1618 | Yes |
15 | ANKFY1 | NA | 1678 | 0.477 | 0.1700 | Yes |
16 | VPS13A | NA | 1683 | 0.477 | 0.1815 | Yes |
17 | CACNG8 | NA | 1776 | 0.469 | 0.1913 | Yes |
18 | PIK3R4 | NA | 1840 | 0.466 | 0.2016 | Yes |
19 | NAGPA | NA | 2030 | 0.454 | 0.2092 | Yes |
20 | HGSNAT | NA | 2086 | 0.451 | 0.2193 | Yes |
21 | IGF2R | NA | 2327 | 0.439 | 0.2256 | Yes |
22 | VPS4B | NA | 2362 | 0.438 | 0.2357 | Yes |
23 | VPS39 | NA | 2386 | 0.436 | 0.2459 | Yes |
24 | ZFYVE16 | NA | 2596 | 0.427 | 0.2525 | Yes |
25 | VTI1B | NA | 2653 | 0.424 | 0.2619 | Yes |
26 | GNPTAB | NA | 2681 | 0.423 | 0.2717 | Yes |
27 | AP3D1 | NA | 2825 | 0.416 | 0.2793 | Yes |
28 | SNX16 | NA | 2839 | 0.416 | 0.2892 | Yes |
29 | TMEM50B | NA | 2913 | 0.413 | 0.2980 | Yes |
30 | MTM1 | NA | 2916 | 0.412 | 0.3081 | Yes |
31 | RBSN | NA | 3041 | 0.408 | 0.3158 | Yes |
32 | VPS11 | NA | 3042 | 0.408 | 0.3257 | Yes |
33 | VPS54 | NA | 3178 | 0.403 | 0.3331 | Yes |
34 | VTA1 | NA | 3200 | 0.402 | 0.3426 | Yes |
35 | SCARB2 | NA | 3276 | 0.399 | 0.3510 | Yes |
36 | STAM | NA | 3298 | 0.398 | 0.3603 | Yes |
37 | VPS41 | NA | 3371 | 0.396 | 0.3687 | Yes |
38 | VPS35 | NA | 3595 | 0.388 | 0.3741 | Yes |
39 | LRP1 | NA | 3758 | 0.382 | 0.3804 | Yes |
40 | HOOK2 | NA | 3802 | 0.380 | 0.3889 | Yes |
41 | CLEC16A | NA | 3849 | 0.378 | 0.3974 | Yes |
42 | VAMP7 | NA | 3864 | 0.378 | 0.4063 | Yes |
43 | TMEM106B | NA | 3997 | 0.374 | 0.4131 | Yes |
44 | CHMP1B | NA | 4091 | 0.371 | 0.4205 | Yes |
45 | VPS53 | NA | 4159 | 0.369 | 0.4283 | Yes |
46 | HGS | NA | 4170 | 0.369 | 0.4371 | Yes |
47 | SNX27 | NA | 4474 | 0.360 | 0.4404 | Yes |
48 | VPS4A | NA | 4481 | 0.360 | 0.4491 | Yes |
49 | AP3B1 | NA | 4493 | 0.360 | 0.4576 | Yes |
50 | VPS13C | NA | 4714 | 0.353 | 0.4622 | Yes |
51 | VPS52 | NA | 4991 | 0.346 | 0.4656 | Yes |
52 | EPG5 | NA | 5021 | 0.345 | 0.4735 | Yes |
53 | VPS16 | NA | 5144 | 0.342 | 0.4797 | Yes |
54 | NDFIP2 | NA | 5208 | 0.340 | 0.4868 | Yes |
55 | SORL1 | NA | 5570 | 0.331 | 0.4883 | Yes |
56 | GOSR2 | NA | 5659 | 0.329 | 0.4947 | Yes |
57 | GRN | NA | 5685 | 0.328 | 0.5023 | Yes |
58 | GGA3 | NA | 5841 | 0.324 | 0.5073 | Yes |
59 | CHMP7 | NA | 5923 | 0.322 | 0.5137 | Yes |
60 | NDFIP1 | NA | 6054 | 0.319 | 0.5192 | Yes |
61 | CHMP3 | NA | 6062 | 0.319 | 0.5268 | Yes |
62 | TRAK2 | NA | 6152 | 0.317 | 0.5330 | Yes |
63 | ATG14 | NA | 6374 | 0.312 | 0.5366 | Yes |
64 | HOOK3 | NA | 6481 | 0.310 | 0.5422 | Yes |
65 | UBXN6 | NA | 6837 | 0.302 | 0.5431 | Yes |
66 | SCYL2 | NA | 6851 | 0.302 | 0.5502 | Yes |
67 | GCC2 | NA | 6886 | 0.301 | 0.5570 | Yes |
68 | PINK1 | NA | 7180 | 0.296 | 0.5588 | Yes |
69 | EHD3 | NA | 7201 | 0.295 | 0.5657 | Yes |
70 | FAM160A2 | NA | 7241 | 0.294 | 0.5722 | Yes |
71 | SPTBN5 | NA | 7384 | 0.291 | 0.5767 | Yes |
72 | BECN1 | NA | 7659 | 0.286 | 0.5786 | Yes |
73 | VPS51 | NA | 7737 | 0.284 | 0.5842 | Yes |
74 | VPS37B | NA | 7744 | 0.284 | 0.5910 | Yes |
75 | M6PR | NA | 8553 | 0.269 | 0.5828 | Yes |
76 | SLC46A3 | NA | 8707 | 0.267 | 0.5865 | Yes |
77 | RAB12 | NA | 8709 | 0.267 | 0.5930 | Yes |
78 | CCDC91 | NA | 8717 | 0.266 | 0.5994 | Yes |
79 | USE1 | NA | 8738 | 0.266 | 0.6055 | Yes |
80 | PSAP | NA | 8774 | 0.265 | 0.6114 | Yes |
81 | ATP6V0D1 | NA | 8790 | 0.265 | 0.6176 | Yes |
82 | BIN1 | NA | 9229 | 0.257 | 0.6158 | Yes |
83 | CHMP1A | NA | 9313 | 0.256 | 0.6206 | Yes |
84 | VIPAS39 | NA | 9480 | 0.253 | 0.6237 | Yes |
85 | SNAPIN | NA | 9815 | 0.247 | 0.6236 | Yes |
86 | CHMP4C | NA | 10232 | 0.241 | 0.6219 | Yes |
87 | AP1G2 | NA | 10565 | 0.235 | 0.6215 | Yes |
88 | RNF215 | NA | 10826 | 0.231 | 0.6224 | Yes |
89 | ARSB | NA | 10951 | 0.230 | 0.6258 | Yes |
90 | GAK | NA | 11664 | 0.219 | 0.6180 | No |
91 | LAMP1 | NA | 12298 | 0.211 | 0.6116 | No |
92 | CDX2 | NA | 12825 | 0.203 | 0.6069 | No |
93 | MGRN1 | NA | 13296 | 0.196 | 0.6031 | No |
94 | HOOK1 | NA | 13374 | 0.195 | 0.6064 | No |
95 | VCP | NA | 13405 | 0.195 | 0.6106 | No |
96 | SMURF1 | NA | 14194 | 0.184 | 0.6007 | No |
97 | ATP6V0D2 | NA | 14824 | 0.176 | 0.5934 | No |
98 | MON1A | NA | 15112 | 0.172 | 0.5924 | No |
99 | CHMP6 | NA | 15167 | 0.172 | 0.5956 | No |
100 | AP4M1 | NA | 15375 | 0.169 | 0.5959 | No |
101 | DTX3L | NA | 15470 | 0.168 | 0.5983 | No |
102 | LRRK2 | NA | 15895 | 0.163 | 0.5945 | No |
103 | SNF8 | NA | 16020 | 0.161 | 0.5962 | No |
104 | RAB7B | NA | 16457 | 0.156 | 0.5920 | No |
105 | HMGXB4 | NA | 16535 | 0.155 | 0.5943 | No |
106 | LAMP2 | NA | 17036 | 0.149 | 0.5888 | No |
107 | CLU | NA | 17160 | 0.147 | 0.5901 | No |
108 | AKTIP | NA | 17403 | 0.144 | 0.5892 | No |
109 | VPS25 | NA | 17561 | 0.142 | 0.5898 | No |
110 | LEPROT | NA | 17839 | 0.139 | 0.5881 | No |
111 | CLN3 | NA | 18819 | 0.126 | 0.5732 | No |
112 | TSG101 | NA | 19066 | 0.123 | 0.5717 | No |
113 | CHMP4A | NA | 20050 | 0.111 | 0.5564 | No |
114 | BECN2 | NA | 20324 | 0.107 | 0.5540 | No |
115 | NEDD4 | NA | 20989 | 0.100 | 0.5442 | No |
116 | TMEM50A | NA | 22226 | 0.086 | 0.5236 | No |
117 | RNF157 | NA | 22726 | 0.080 | 0.5164 | No |
118 | CACNG4 | NA | 23131 | 0.076 | 0.5108 | No |
119 | GPRASP1 | NA | 23247 | 0.075 | 0.5106 | No |
120 | DENND3 | NA | 23519 | 0.072 | 0.5073 | No |
121 | VTI1A | NA | 23852 | 0.068 | 0.5029 | No |
122 | NPC1 | NA | 23944 | 0.068 | 0.5029 | No |
123 | MVB12A | NA | 24209 | 0.065 | 0.4996 | No |
124 | CHMP4B | NA | 25030 | 0.057 | 0.4860 | No |
125 | VPS28 | NA | 28859 | 0.027 | 0.4163 | No |
126 | LYST | NA | 29633 | 0.022 | 0.4027 | No |
127 | RAB7A | NA | 30138 | 0.020 | 0.3939 | No |
128 | SLC15A4 | NA | 31228 | 0.014 | 0.3742 | No |
129 | CHMP2B | NA | 33749 | 0.003 | 0.3280 | No |
130 | HSPA1A | NA | 39308 | -0.003 | 0.2260 | No |
131 | HSPA8 | NA | 39913 | -0.011 | 0.2151 | No |
132 | VPS37D | NA | 41041 | -0.024 | 0.1950 | No |
133 | PCDHGA3 | NA | 41491 | -0.029 | 0.1875 | No |
134 | PCSK9 | NA | 42943 | -0.048 | 0.1620 | No |
135 | CHMP5 | NA | 43360 | -0.053 | 0.1557 | No |
136 | ADRB2 | NA | 43362 | -0.053 | 0.1570 | No |
137 | CACNG7 | NA | 43846 | -0.060 | 0.1496 | No |
138 | CHMP2A | NA | 44709 | -0.072 | 0.1355 | No |
139 | CACNG2 | NA | 44804 | -0.073 | 0.1356 | No |
140 | C9orf72 | NA | 44870 | -0.074 | 0.1362 | No |
141 | VPS37C | NA | 44935 | -0.075 | 0.1369 | No |
142 | CACNG5 | NA | 45981 | -0.091 | 0.1199 | No |
143 | STX8 | NA | 46000 | -0.091 | 0.1218 | No |
144 | RILP | NA | 46105 | -0.093 | 0.1221 | No |
145 | LAPTM5 | NA | 46576 | -0.100 | 0.1160 | No |
146 | WASH3P | NA | 46600 | -0.101 | 0.1180 | No |
147 | ARF1 | NA | 46706 | -0.102 | 0.1186 | No |
148 | VPS37A | NA | 46974 | -0.107 | 0.1163 | No |
149 | RHOB | NA | 51638 | -0.206 | 0.0357 | No |
150 | LEPROTL1 | NA | 52015 | -0.215 | 0.0340 | No |
151 | CACNG3 | NA | 53420 | -0.269 | 0.0148 | No |
152 | CHMP4BP1 | NA | 53453 | -0.272 | 0.0209 | No |