Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Breast.Breast.cls #Breast_30-39_versus_Breast_70-79.Breast.cls #Breast_30-39_versus_Breast_70-79_repos |
| Phenotype | Breast.cls#Breast_30-39_versus_Breast_70-79_repos |
| Upregulated in class | Breast_30-39 |
| GeneSet | GOBP_VESICLE_DOCKING_INVOLVED_IN_EXOCYTOSIS |
| Enrichment Score (ES) | 0.6467986 |
| Normalized Enrichment Score (NES) | 1.7158341 |
| Nominal p-value | 0.0018484289 |
| FDR q-value | 0.38142323 |
| FWER p-Value | 0.599 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | UNC13B | NA | 56 | 0.761 | 0.0679 | Yes |
| 2 | YKT6 | NA | 257 | 0.652 | 0.1233 | Yes |
| 3 | VPS33A | NA | 335 | 0.629 | 0.1788 | Yes |
| 4 | VPS18 | NA | 571 | 0.582 | 0.2272 | Yes |
| 5 | STX1B | NA | 964 | 0.534 | 0.2683 | Yes |
| 6 | VPS45 | NA | 1012 | 0.529 | 0.3153 | Yes |
| 7 | SNPH | NA | 2257 | 0.443 | 0.3326 | Yes |
| 8 | VTI1B | NA | 2653 | 0.424 | 0.3638 | Yes |
| 9 | KCNB1 | NA | 2659 | 0.424 | 0.4021 | Yes |
| 10 | VPS11 | NA | 3042 | 0.408 | 0.4320 | Yes |
| 11 | RAB3D | NA | 4575 | 0.357 | 0.4363 | Yes |
| 12 | SCFD1 | NA | 4638 | 0.355 | 0.4673 | Yes |
| 13 | CTBP2 | NA | 5748 | 0.326 | 0.4765 | Yes |
| 14 | STXBP3 | NA | 6567 | 0.308 | 0.4894 | Yes |
| 15 | BLOC1S6 | NA | 6633 | 0.306 | 0.5159 | Yes |
| 16 | VPS33B | NA | 7509 | 0.289 | 0.5260 | Yes |
| 17 | EXOC6B | NA | 7884 | 0.281 | 0.5446 | Yes |
| 18 | STX3 | NA | 8358 | 0.273 | 0.5607 | Yes |
| 19 | RAB12 | NA | 8709 | 0.267 | 0.5784 | Yes |
| 20 | EXOC4 | NA | 9725 | 0.249 | 0.5823 | Yes |
| 21 | UNC13A | NA | 10434 | 0.238 | 0.5908 | Yes |
| 22 | PPFIA3 | NA | 10454 | 0.237 | 0.6120 | Yes |
| 23 | STX1A | NA | 11367 | 0.224 | 0.6155 | Yes |
| 24 | RAB10 | NA | 11572 | 0.221 | 0.6317 | Yes |
| 25 | RAB15 | NA | 11822 | 0.217 | 0.6468 | Yes |
| 26 | UNC13C | NA | 18788 | 0.126 | 0.5306 | No |
| 27 | RAB13 | NA | 19405 | 0.119 | 0.5300 | No |
| 28 | STXBP2 | NA | 19511 | 0.117 | 0.5387 | No |
| 29 | RAB3B | NA | 21086 | 0.098 | 0.5188 | No |
| 30 | SCFD2 | NA | 24062 | 0.066 | 0.4702 | No |
| 31 | VAMP3 | NA | 24404 | 0.063 | 0.4697 | No |
| 32 | RABEPK | NA | 26209 | 0.046 | 0.4408 | No |
| 33 | CFTR | NA | 27882 | 0.033 | 0.4131 | No |
| 34 | SNAP25 | NA | 28251 | 0.031 | 0.4092 | No |
| 35 | SYTL2 | NA | 29210 | 0.025 | 0.3939 | No |
| 36 | RAB8B | NA | 30323 | 0.019 | 0.3752 | No |
| 37 | EXOC6 | NA | 32898 | 0.007 | 0.3286 | No |
| 38 | PLEK | NA | 39622 | -0.007 | 0.2060 | No |
| 39 | RAB8A | NA | 42154 | -0.037 | 0.1630 | No |
| 40 | RAB3C | NA | 43645 | -0.057 | 0.1408 | No |
| 41 | STXBP1 | NA | 47007 | -0.108 | 0.0889 | No |
| 42 | RAB3A | NA | 47590 | -0.118 | 0.0889 | No |
| 43 | RALB | NA | 51449 | -0.201 | 0.0364 | No |
| 44 | CPLX2 | NA | 52702 | -0.234 | 0.0346 | No |
