Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Thyroid.Thyroid.cls #Thyroid_30-39_versus_Thyroid_70-79.Thyroid.cls #Thyroid_30-39_versus_Thyroid_70-79_repos |
| Phenotype | Thyroid.cls#Thyroid_30-39_versus_Thyroid_70-79_repos |
| Upregulated in class | Thyroid_30-39 |
| GeneSet | GOBP_ADENYLATE_CYCLASE_ACTIVATING_ADRENERGIC_RECEPTOR_SIGNALING_PATHWAY |
| Enrichment Score (ES) | 0.51827675 |
| Normalized Enrichment Score (NES) | 1.2892772 |
| Nominal p-value | 0.15224913 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.999 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | ADRA1B | NA | 257 | 0.388 | 0.0966 | Yes |
| 2 | PDE4D | NA | 639 | 0.321 | 0.1736 | Yes |
| 3 | PLN | NA | 917 | 0.293 | 0.2451 | Yes |
| 4 | ADRA2C | NA | 1490 | 0.252 | 0.3005 | Yes |
| 5 | ADRB2 | NA | 2524 | 0.209 | 0.3361 | Yes |
| 6 | RAPGEF2 | NA | 2895 | 0.196 | 0.3804 | Yes |
| 7 | CHGA | NA | 3323 | 0.183 | 0.4204 | Yes |
| 8 | DRD5 | NA | 4299 | 0.157 | 0.4435 | Yes |
| 9 | ADRA1A | NA | 5698 | 0.129 | 0.4515 | Yes |
| 10 | ADRA2A | NA | 5817 | 0.126 | 0.4823 | Yes |
| 11 | GPR101 | NA | 5942 | 0.124 | 0.5125 | Yes |
| 12 | DRD3 | NA | 7496 | 0.099 | 0.5099 | Yes |
| 13 | ADRA1D | NA | 8289 | 0.088 | 0.5183 | Yes |
| 14 | DRD1 | NA | 12995 | 0.037 | 0.4417 | No |
| 15 | ADRB3 | NA | 13420 | 0.033 | 0.4426 | No |
| 16 | MIR1-1 | NA | 20140 | 0.000 | 0.3195 | No |
| 17 | ARRDC3 | NA | 26568 | -0.014 | 0.2054 | No |
| 18 | ADRA2B | NA | 27188 | -0.020 | 0.1993 | No |
| 19 | AKAP13 | NA | 30705 | -0.054 | 0.1489 | No |
| 20 | GNAI2 | NA | 34078 | -0.087 | 0.1098 | No |
| 21 | ADCY9 | NA | 38562 | -0.133 | 0.0623 | No |
| 22 | PDE4B | NA | 39448 | -0.142 | 0.0832 | No |
| 23 | ATP2B4 | NA | 40979 | -0.160 | 0.0970 | No |
| 24 | ADRB1 | NA | 46316 | -0.235 | 0.0607 | No |
| 25 | DRD2 | NA | 51379 | -0.348 | 0.0589 | No |
