Dataset | Thyroid.Thyroid.cls #Thyroid_30-39_versus_Thyroid_70-79.Thyroid.cls #Thyroid_30-39_versus_Thyroid_70-79_repos |
Phenotype | Thyroid.cls#Thyroid_30-39_versus_Thyroid_70-79_repos |
Upregulated in class | Thyroid_30-39 |
GeneSet | GOBP_COMPLEMENT_ACTIVATION |
Enrichment Score (ES) | 0.76333016 |
Normalized Enrichment Score (NES) | 1.5421726 |
Nominal p-value | 0.05061082 |
FDR q-value | 1.0 |
FWER p-Value | 0.916 |
SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|
1 | C1QC | NA | 22 | 0.551 | 0.0163 | Yes |
2 | C1QA | NA | 28 | 0.541 | 0.0325 | Yes |
3 | C1QB | NA | 33 | 0.534 | 0.0486 | Yes |
4 | C3AR1 | NA | 46 | 0.512 | 0.0639 | Yes |
5 | C5AR2 | NA | 167 | 0.419 | 0.0744 | Yes |
6 | IGHV2-70 | NA | 266 | 0.384 | 0.0842 | Yes |
7 | VSIG4 | NA | 383 | 0.359 | 0.0929 | Yes |
8 | IGHV3-20 | NA | 541 | 0.333 | 0.1001 | Yes |
9 | CFP | NA | 562 | 0.330 | 0.1097 | Yes |
10 | IGKV4-1 | NA | 570 | 0.329 | 0.1195 | Yes |
11 | IGHG3 | NA | 685 | 0.317 | 0.1270 | Yes |
12 | IGHV3-11 | NA | 702 | 0.315 | 0.1363 | Yes |
13 | IGHV3-72 | NA | 821 | 0.303 | 0.1433 | Yes |
14 | IGLV2-23 | NA | 825 | 0.303 | 0.1524 | Yes |
15 | IGHG2 | NA | 846 | 0.301 | 0.1611 | Yes |
16 | C4BPB | NA | 906 | 0.294 | 0.1689 | Yes |
17 | IGKV3-15 | NA | 938 | 0.291 | 0.1771 | Yes |
18 | IGHV1-69D | NA | 947 | 0.290 | 0.1858 | Yes |
19 | IGLV3-25 | NA | 962 | 0.289 | 0.1942 | Yes |
20 | IGHV1-3 | NA | 1000 | 0.286 | 0.2022 | Yes |
21 | IGHV1-69-2 | NA | 1014 | 0.284 | 0.2106 | Yes |
22 | IGKV2-40 | NA | 1015 | 0.284 | 0.2192 | Yes |
23 | IGKV2-30 | NA | 1114 | 0.276 | 0.2257 | Yes |
24 | IGHV5-51 | NA | 1135 | 0.274 | 0.2336 | Yes |
25 | IGHG1 | NA | 1146 | 0.273 | 0.2417 | Yes |
26 | IGKV1-16 | NA | 1158 | 0.272 | 0.2497 | Yes |
27 | IGHV3-49 | NA | 1199 | 0.270 | 0.2572 | Yes |
28 | IGHV3-30 | NA | 1213 | 0.269 | 0.2651 | Yes |
29 | IGHV1-18 | NA | 1236 | 0.267 | 0.2727 | Yes |
30 | IGKV1-5 | NA | 1241 | 0.267 | 0.2807 | Yes |
31 | IGHV3-74 | NA | 1243 | 0.267 | 0.2888 | Yes |
32 | CFHR4 | NA | 1268 | 0.265 | 0.2964 | Yes |
33 | IGLV1-47 | NA | 1327 | 0.261 | 0.3032 | Yes |
34 | IGKV1D-33 | NA | 1341 | 0.260 | 0.3108 | Yes |
35 | IGHV1OR15-1 | NA | 1378 | 0.258 | 0.3180 | Yes |
36 | IGHV4-4 | NA | 1379 | 0.258 | 0.3258 | Yes |
37 | IGLV3-21 | NA | 1420 | 0.255 | 0.3327 | Yes |
38 | IGLV3-1 | NA | 1435 | 0.255 | 0.3402 | Yes |
39 | IGHV4-59 | NA | 1451 | 0.254 | 0.3476 | Yes |
40 | IGHV3-21 | NA | 1460 | 0.253 | 0.3551 | Yes |
41 | IGHV3-48 | NA | 1478 | 0.252 | 0.3624 | Yes |
42 | IGHV3-23 | NA | 1510 | 0.251 | 0.3694 | Yes |
43 | IGKV1-12 | NA | 1511 | 0.251 | 0.3770 | Yes |
44 | IGHV2-5 | NA | 1536 | 0.249 | 0.3841 | Yes |
45 | C2 | NA | 1543 | 0.249 | 0.3915 | Yes |
46 | IGHV3-7 | NA | 1550 | 0.248 | 0.3989 | Yes |
47 | IGLV7-43 | NA | 1552 | 0.248 | 0.4064 | Yes |
48 | IGKV3-20 | NA | 1555 | 0.248 | 0.4139 | Yes |
49 | IGHV3-15 | NA | 1586 | 0.246 | 0.4208 | Yes |
50 | IGLC3 | NA | 1602 | 0.246 | 0.4279 | Yes |
51 | IGHV2-26 | NA | 1612 | 0.245 | 0.4352 | Yes |
52 | IGHV4-61 | NA | 1690 | 0.242 | 0.4411 | Yes |
53 | IGHD | NA | 1697 | 0.241 | 0.4483 | Yes |
54 | IGLV2-8 | NA | 1729 | 0.239 | 0.4549 | Yes |
55 | IGKV2D-30 | NA | 1768 | 0.238 | 0.4614 | Yes |
56 | IGKV1D-39 | NA | 1794 | 0.236 | 0.4681 | Yes |
57 | IGLV2-11 | NA | 1811 | 0.236 | 0.4749 | Yes |
58 | IGHV4-34 | NA | 1818 | 0.235 | 0.4819 | Yes |
59 | IGHG4 | NA | 1903 | 0.232 | 0.4874 | Yes |
60 | IGHV3-64 | NA | 1932 | 0.231 | 0.4939 | Yes |
61 | IGHV2-70D | NA | 1979 | 0.229 | 0.4999 | Yes |
62 | IGHV3-35 | NA | 2011 | 0.228 | 0.5063 | Yes |
63 | IGLV2-14 | NA | 2033 | 0.227 | 0.5128 | Yes |
64 | IGLV1-51 | NA | 2044 | 0.227 | 0.5194 | Yes |
65 | IGKC | NA | 2057 | 0.226 | 0.5261 | Yes |
66 | IGKV2D-28 | NA | 2099 | 0.225 | 0.5321 | Yes |
67 | IGHV3-13 | NA | 2110 | 0.224 | 0.5387 | Yes |
68 | IGKV1-39 | NA | 2126 | 0.224 | 0.5452 | Yes |
69 | IGLV3-19 | NA | 2132 | 0.224 | 0.5519 | Yes |
70 | IGLV3-27 | NA | 2209 | 0.221 | 0.5571 | Yes |
71 | IGKV5-2 | NA | 2231 | 0.220 | 0.5634 | Yes |
72 | IGHV1-24 | NA | 2244 | 0.219 | 0.5698 | Yes |
73 | IGHV3-73 | NA | 2283 | 0.217 | 0.5757 | Yes |
74 | CD5L | NA | 2335 | 0.215 | 0.5812 | Yes |
75 | IGKV3D-20 | NA | 2398 | 0.213 | 0.5865 | Yes |
76 | IGLV1-40 | NA | 2400 | 0.213 | 0.5930 | Yes |
77 | IGHV3-33 | NA | 2419 | 0.212 | 0.5990 | Yes |
78 | IGHV1-58 | NA | 2539 | 0.208 | 0.6032 | Yes |
79 | IGLC2 | NA | 2547 | 0.208 | 0.6093 | Yes |
80 | IGHV3-38 | NA | 2548 | 0.208 | 0.6156 | Yes |
81 | IGKV3D-11 | NA | 2573 | 0.207 | 0.6214 | Yes |
82 | IGLC6 | NA | 2574 | 0.207 | 0.6277 | Yes |
83 | IGHV7-81 | NA | 2622 | 0.205 | 0.6330 | Yes |
84 | IGHV1-69 | NA | 2627 | 0.205 | 0.6391 | Yes |
85 | IGLL1 | NA | 2697 | 0.202 | 0.6440 | Yes |
86 | IGKV2-28 | NA | 2754 | 0.201 | 0.6490 | Yes |
87 | SERPING1 | NA | 2784 | 0.199 | 0.6545 | Yes |
88 | IGKV1-17 | NA | 2814 | 0.199 | 0.6600 | Yes |
89 | IGHV4-39 | NA | 2816 | 0.199 | 0.6660 | Yes |
90 | IGKV1D-12 | NA | 2817 | 0.199 | 0.6720 | Yes |
91 | IGLC1 | NA | 2899 | 0.195 | 0.6764 | Yes |
92 | IGHV3-43 | NA | 3029 | 0.191 | 0.6798 | Yes |
93 | A2M | NA | 3063 | 0.190 | 0.6850 | Yes |
94 | IGHV4-28 | NA | 3075 | 0.190 | 0.6905 | Yes |
95 | C9 | NA | 3242 | 0.185 | 0.6930 | Yes |
96 | CR2 | NA | 3270 | 0.184 | 0.6981 | Yes |
97 | IGLV1-44 | NA | 3311 | 0.183 | 0.7029 | Yes |
98 | IGHV1-45 | NA | 3364 | 0.182 | 0.7075 | Yes |
99 | PROS1 | NA | 3365 | 0.182 | 0.7130 | Yes |
100 | IGHV7-4-1 | NA | 3393 | 0.181 | 0.7179 | Yes |
101 | IGHV3-16 | NA | 3394 | 0.181 | 0.7234 | Yes |
102 | IGHV3-53 | NA | 3723 | 0.172 | 0.7226 | Yes |
103 | IGHM | NA | 3785 | 0.170 | 0.7266 | Yes |
104 | MASP2 | NA | 3857 | 0.168 | 0.7303 | Yes |
105 | IGHV6-1 | NA | 3991 | 0.165 | 0.7329 | Yes |
106 | IGHV5-10-1 | NA | 4000 | 0.164 | 0.7377 | Yes |
107 | CFHR1 | NA | 4045 | 0.163 | 0.7418 | Yes |
108 | IGHV4-31 | NA | 4069 | 0.163 | 0.7463 | Yes |
109 | IGLV6-57 | NA | 4269 | 0.158 | 0.7474 | Yes |
110 | IGHV3-66 | NA | 4327 | 0.156 | 0.7511 | Yes |
111 | C5 | NA | 4330 | 0.156 | 0.7558 | Yes |
112 | MASP1 | NA | 4355 | 0.156 | 0.7601 | Yes |
113 | IGKV2-29 | NA | 4573 | 0.151 | 0.7606 | Yes |
114 | C4BPA | NA | 4672 | 0.149 | 0.7633 | Yes |
115 | CPB2 | NA | 4984 | 0.143 | 0.7619 | No |
116 | CR1 | NA | 5194 | 0.139 | 0.7623 | No |
117 | CRP | NA | 5763 | 0.127 | 0.7557 | No |
118 | C1QBP | NA | 5767 | 0.127 | 0.7595 | No |
119 | C1S | NA | 5931 | 0.124 | 0.7602 | No |
120 | TRBC1 | NA | 6565 | 0.114 | 0.7521 | No |
121 | IGHV3-64D | NA | 7005 | 0.107 | 0.7472 | No |
122 | IGLC7 | NA | 7419 | 0.100 | 0.7427 | No |
123 | TRBC2 | NA | 7436 | 0.100 | 0.7454 | No |
124 | CD19 | NA | 7476 | 0.099 | 0.7477 | No |
125 | KRT1 | NA | 7728 | 0.096 | 0.7459 | No |
126 | C4A | NA | 9029 | 0.078 | 0.7244 | No |
127 | MFAP4 | NA | 9782 | 0.069 | 0.7127 | No |
128 | RGCC | NA | 10193 | 0.064 | 0.7071 | No |
129 | TRDC | NA | 10333 | 0.062 | 0.7064 | No |
130 | C1R | NA | 10343 | 0.062 | 0.7081 | No |
131 | CD59 | NA | 10439 | 0.061 | 0.7082 | No |
132 | C6 | NA | 10692 | 0.058 | 0.7053 | No |
133 | FCN3 | NA | 11632 | 0.049 | 0.6896 | No |
134 | CFH | NA | 11950 | 0.046 | 0.6851 | No |
135 | C4B | NA | 12255 | 0.043 | 0.6808 | No |
136 | CFHR5 | NA | 12663 | 0.039 | 0.6745 | No |
137 | C8A | NA | 12895 | 0.038 | 0.6714 | No |
138 | C8B | NA | 15305 | 0.020 | 0.6278 | No |
139 | F2 | NA | 15633 | 0.018 | 0.6223 | No |
140 | CFHR2 | NA | 15845 | 0.017 | 0.6189 | No |
141 | IGHA1 | NA | 16252 | 0.015 | 0.6119 | No |
142 | FCN1 | NA | 18571 | 0.004 | 0.5694 | No |
143 | CPN1 | NA | 18624 | 0.004 | 0.5686 | No |
144 | COLEC10 | NA | 18923 | 0.002 | 0.5632 | No |
145 | MIR520E | NA | 23439 | 0.000 | 0.4802 | No |
146 | MIR520B | NA | 24057 | 0.000 | 0.4689 | No |
147 | C7 | NA | 25876 | -0.007 | 0.4357 | No |
148 | IGHA2 | NA | 25884 | -0.007 | 0.4358 | No |
149 | C3 | NA | 26097 | -0.010 | 0.4322 | No |
150 | PHB | NA | 26646 | -0.015 | 0.4226 | No |
151 | CPN2 | NA | 27129 | -0.019 | 0.4143 | No |
152 | APCS | NA | 27223 | -0.020 | 0.4132 | No |
153 | FCN2 | NA | 28546 | -0.032 | 0.3899 | No |
154 | CFD | NA | 31789 | -0.064 | 0.3323 | No |
155 | CR1L | NA | 32281 | -0.069 | 0.3254 | No |
156 | CD55 | NA | 32929 | -0.076 | 0.3158 | No |
157 | VTN | NA | 34499 | -0.091 | 0.2897 | No |
158 | CLU | NA | 35202 | -0.098 | 0.2798 | No |
159 | IL1B | NA | 35437 | -0.100 | 0.2785 | No |
160 | C5AR1 | NA | 37017 | -0.116 | 0.2530 | No |
161 | MBL2 | NA | 38004 | -0.126 | 0.2387 | No |
162 | C1RL | NA | 38743 | -0.135 | 0.2292 | No |
163 | CFB | NA | 42111 | -0.175 | 0.1726 | No |
164 | CFI | NA | 42287 | -0.177 | 0.1747 | No |
165 | COLEC11 | NA | 43431 | -0.192 | 0.1595 | No |
166 | SUSD4 | NA | 45653 | -0.225 | 0.1255 | No |
167 | C8G | NA | 48988 | -0.286 | 0.0729 | No |
168 | CD81 | NA | 49796 | -0.305 | 0.0673 | No |
169 | CD46 | NA | 50667 | -0.327 | 0.0612 | No |
170 | IGHE | NA | 51792 | -0.361 | 0.0514 | No |