Details for gene set GOBP_DEFENSE_RESPONSE_TO

Table: GSEA Results Summary

Dataset	Thyroid.Thyroid.cls #Thyroid_30-39_versus_Thyroid_70-79.Thyroid.cls #Thyroid_30-39_versus_Thyroid_70-79_repos
Phenotype	Thyroid.cls#Thyroid_30-39_versus_Thyroid_70-79_repos
Upregulated in class	Thyroid_30-39
GeneSet	GOBP_DEFENSE_RESPONSE_TO_BACTERIUM
Enrichment Score (ES)	0.41305098
Normalized Enrichment Score (NES)	1.1335667
Nominal p-value	0.37521222
FDR q-value	1.0
FWER p-Value	1.0

Table: GSEA details [plain text format]
	SYMBOL	TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	GSDMC	NA	59	0.493	0.0088	Yes
2	RNASE6	NA	92	0.466	0.0176	Yes
3	LYZ	NA	157	0.424	0.0250	Yes
4	MPEG1	NA	180	0.415	0.0329	Yes
5	CD4	NA	181	0.413	0.0412	Yes
6	IGHV2-70	NA	266	0.384	0.0474	Yes
7	CD160	NA	413	0.354	0.0519	Yes
8	IGHV3-20	NA	541	0.333	0.0562	Yes
9	NLRC4	NA	558	0.331	0.0626	Yes
10	CFP	NA	562	0.330	0.0692	Yes
11	HAVCR2	NA	641	0.321	0.0742	Yes
12	IGHG3	NA	685	0.317	0.0798	Yes
13	IGHV3-11	NA	702	0.315	0.0859	Yes
14	PRB3	NA	719	0.313	0.0919	Yes
15	GSDMA	NA	739	0.311	0.0978	Yes
16	IGHV3-72	NA	821	0.303	0.1024	Yes
17	IGHG2	NA	846	0.301	0.1080	Yes
18	FCER1G	NA	868	0.298	0.1136	Yes
19	CD36	NA	926	0.292	0.1185	Yes
20	IGHV1-69D	NA	947	0.290	0.1239	Yes
21	IGHV1-3	NA	1000	0.286	0.1287	Yes
22	IGHV1-69-2	NA	1014	0.284	0.1342	Yes
23	IGHV5-51	NA	1135	0.274	0.1375	Yes
24	IGHG1	NA	1146	0.273	0.1429	Yes
25	IGHV3-49	NA	1199	0.270	0.1473	Yes
26	IGHV3-30	NA	1213	0.269	0.1525	Yes
27	IGHV1-18	NA	1236	0.267	0.1575	Yes
28	IGHV3-74	NA	1243	0.267	0.1627	Yes
29	RNASE3	NA	1348	0.260	0.1661	Yes
30	MYD88	NA	1367	0.259	0.1709	Yes
31	IGHV1OR15-1	NA	1378	0.258	0.1760	Yes
32	IGHV4-4	NA	1379	0.258	0.1811	Yes
33	IGHV4-59	NA	1451	0.254	0.1850	Yes
34	IGHV3-21	NA	1460	0.253	0.1899	Yes
35	IGHV3-48	NA	1478	0.252	0.1947	Yes
36	MR1	NA	1486	0.252	0.1996	Yes
37	IGHV3-23	NA	1510	0.251	0.2042	Yes
38	S100A7	NA	1533	0.249	0.2089	Yes
39	IGHV2-5	NA	1536	0.249	0.2138	Yes
40	IGHV3-7	NA	1550	0.248	0.2186	Yes
41	IGKV3-20	NA	1555	0.248	0.2235	Yes
42	IGHV3-15	NA	1586	0.246	0.2279	Yes
43	IGLC3	NA	1602	0.246	0.2326	Yes
44	IGHV2-26	NA	1612	0.245	0.2374	Yes
45	IGHV4-61	NA	1690	0.242	0.2408	Yes
46	IGHD	NA	1697	0.241	0.2456	Yes
47	FGR	NA	1741	0.239	0.2496	Yes
48	HAMP	NA	1771	0.237	0.2538	Yes
49	TNFSF8	NA	1788	0.237	0.2583	Yes
50	IGHV4-34	NA	1818	0.235	0.2625	Yes
51	IGHG4	NA	1903	0.232	0.2656	Yes
52	TLR4	NA	1930	0.231	0.2698	Yes
53	IGHV3-64	NA	1932	0.231	0.2744	Yes
54	TIRAP	NA	1967	0.229	0.2784	Yes
55	IGHV2-70D	NA	1979	0.229	0.2828	Yes
56	LTF	NA	1983	0.229	0.2874	Yes
57	IGHV3-35	NA	2011	0.228	0.2915	Yes
58	DEFB132	NA	2045	0.227	0.2954	Yes
59	IGKC	NA	2057	0.226	0.2998	Yes
60	IGHV3-13	NA	2110	0.224	0.3033	Yes
61	IGHV1-24	NA	2244	0.219	0.3053	Yes
62	IGHV3-73	NA	2283	0.217	0.3090	Yes
63	PLA2G1B	NA	2366	0.214	0.3118	Yes
64	IGHV3-33	NA	2419	0.212	0.3151	Yes
65	IGHV1-58	NA	2539	0.208	0.3171	Yes
66	IGLC2	NA	2547	0.208	0.3211	Yes
67	IGHV3-38	NA	2548	0.208	0.3253	Yes
68	IGLC6	NA	2574	0.207	0.3290	Yes
69	CXCL13	NA	2612	0.205	0.3325	Yes
70	IGHV7-81	NA	2622	0.205	0.3364	Yes
71	IGHV1-69	NA	2627	0.205	0.3405	Yes
72	IGLL1	NA	2697	0.202	0.3433	Yes
73	ADAMTS5	NA	2710	0.202	0.3471	Yes
74	SYT11	NA	2726	0.201	0.3509	Yes
75	IGHV4-39	NA	2816	0.199	0.3533	Yes
76	IGLC1	NA	2899	0.195	0.3557	Yes
77	PGLYRP4	NA	2962	0.193	0.3584	Yes
78	IGHV3-43	NA	3029	0.191	0.3611	Yes
79	IGHV4-28	NA	3075	0.190	0.3641	Yes
80	MIR140	NA	3211	0.186	0.3653	Yes
81	TLR3	NA	3286	0.184	0.3677	Yes
82	CHGA	NA	3323	0.183	0.3707	Yes
83	IGHV1-45	NA	3364	0.182	0.3736	Yes
84	IGHV7-4-1	NA	3393	0.181	0.3767	Yes
85	IGHV3-16	NA	3394	0.181	0.3804	Yes
86	BPIFA1	NA	3403	0.181	0.3839	Yes
87	TREM2	NA	3542	0.176	0.3849	Yes
88	IGHV3-53	NA	3723	0.172	0.3850	Yes
89	TRAV27	NA	3761	0.171	0.3878	Yes
90	IGHM	NA	3785	0.170	0.3907	Yes
91	IGHV6-1	NA	3991	0.165	0.3903	Yes
92	IGHV5-10-1	NA	4000	0.164	0.3934	Yes
93	AQP1	NA	4034	0.163	0.3961	Yes
94	IGHV4-31	NA	4069	0.163	0.3988	Yes
95	DCD	NA	4115	0.161	0.4012	Yes
96	IGHV3-66	NA	4327	0.156	0.4005	Yes
97	IL7R	NA	4403	0.155	0.4022	Yes
98	NOD2	NA	4498	0.152	0.4035	Yes
99	CTSG	NA	4631	0.149	0.4041	Yes
100	IL10	NA	4670	0.149	0.4064	Yes
101	NLRP10	NA	4673	0.149	0.4093	Yes
102	LTA	NA	5001	0.142	0.4062	Yes
103	ISG15	NA	5512	0.132	0.3994	Yes
104	BPI	NA	5515	0.132	0.4021	Yes
105	CRP	NA	5763	0.127	0.4001	Yes
106	TBK1	NA	5833	0.126	0.4013	Yes
107	SPN	NA	5840	0.126	0.4038	Yes
108	TF	NA	6027	0.123	0.4028	Yes
109	FGA	NA	6108	0.121	0.4038	Yes
110	DEFB4A	NA	6209	0.120	0.4043	Yes
111	CARD9	NA	6229	0.119	0.4064	Yes
112	FGB	NA	6275	0.118	0.4079	Yes
113	PGLYRP3	NA	6455	0.116	0.4070	Yes
114	DEFB118	NA	6515	0.114	0.4082	Yes
115	IL6R	NA	6557	0.114	0.4097	Yes
116	TRBC1	NA	6565	0.114	0.4119	Yes
117	PRKCD	NA	6985	0.107	0.4063	Yes
118	IGHV3-64D	NA	7005	0.107	0.4081	Yes
119	COLEC12	NA	7051	0.106	0.4094	Yes
120	PGC	NA	7162	0.104	0.4095	Yes
121	PYCARD	NA	7352	0.101	0.4081	Yes
122	IGLC7	NA	7419	0.100	0.4089	Yes
123	TRBC2	NA	7436	0.100	0.4106	Yes
124	JCHAIN	NA	7504	0.099	0.4113	Yes
125	IRGM	NA	7519	0.098	0.4131	Yes
126	DEFA6	NA	7799	0.095	0.4098	No
127	SEMG1	NA	7962	0.092	0.4087	No
128	IRF8	NA	8001	0.092	0.4098	No
129	WFDC5	NA	8480	0.085	0.4027	No
130	WFDC13	NA	8526	0.084	0.4036	No
131	VGF	NA	8613	0.083	0.4037	No
132	SLPI	NA	8698	0.082	0.4038	No
133	NAIP	NA	8994	0.078	0.3999	No
134	FPR2	NA	9369	0.074	0.3945	No
135	LALBA	NA	9502	0.072	0.3935	No
136	NR1H4	NA	9816	0.068	0.3891	No
137	RNASE8	NA	10194	0.064	0.3835	No
138	SEMG2	NA	10218	0.064	0.3843	No
139	TRDC	NA	10333	0.062	0.3835	No
140	UMOD	NA	10418	0.061	0.3832	No
141	TLR6	NA	10518	0.060	0.3826	No
142	PLA2G2A	NA	10572	0.060	0.3828	No
143	PLAC8	NA	10674	0.059	0.3821	No
144	DEFB108B	NA	10805	0.057	0.3809	No
145	SFTPD	NA	10942	0.056	0.3795	No
146	IL23R	NA	10943	0.056	0.3806	No
147	CST11	NA	11468	0.050	0.3720	No
148	DEFA5	NA	11898	0.046	0.3650	No
149	GBP7	NA	12061	0.045	0.3629	No
150	ADAM17	NA	12310	0.042	0.3592	No
151	DEFA4	NA	12325	0.042	0.3598	No
152	SLAMF8	NA	12688	0.039	0.3539	No
153	EPPIN	NA	12690	0.039	0.3547	No
154	MIR181B1	NA	12815	0.038	0.3532	No
155	DEFB135	NA	13211	0.035	0.3466	No
156	SIGLEC16	NA	13367	0.034	0.3444	No
157	ZG16	NA	13391	0.034	0.3447	No
158	KRT6A	NA	13606	0.032	0.3414	No
159	SSC5D	NA	13642	0.032	0.3414	No
160	ELANE	NA	13717	0.031	0.3406	No
161	WFDC10A	NA	13757	0.031	0.3405	No
162	SYK	NA	14202	0.028	0.3329	No
163	IL17F	NA	14335	0.027	0.3310	No
164	STAB1	NA	14649	0.024	0.3257	No
165	LCE3A	NA	14745	0.024	0.3245	No
166	DEFB106B	NA	14798	0.024	0.3240	No
167	DEFB125	NA	15456	0.019	0.3123	No
168	ARG2	NA	15513	0.019	0.3116	No
169	IL17A	NA	15583	0.018	0.3107	No
170	F2	NA	15633	0.018	0.3102	No
171	SPAG11B	NA	15971	0.016	0.3043	No
172	RAG2	NA	16005	0.016	0.3040	No
173	HP	NA	16048	0.016	0.3035	No
174	DEFB121	NA	16077	0.015	0.3033	No
175	DEFB133	NA	16114	0.015	0.3030	No
176	IGHA1	NA	16252	0.015	0.3007	No
177	DEFB136	NA	16255	0.015	0.3010	No
178	IL12A	NA	16263	0.014	0.3011	No
179	DEFB129	NA	16333	0.014	0.3002	No
180	IL22RA1	NA	16499	0.013	0.2974	No
181	HTN3	NA	16717	0.012	0.2936	No
182	GBP4	NA	17869	0.007	0.2726	No
183	LACRT	NA	18210	0.005	0.2664	No
184	DEFB126	NA	18240	0.005	0.2660	No
185	GBP6	NA	18332	0.005	0.2644	No
186	SPAG11A	NA	18351	0.005	0.2642	No
187	HTN1	NA	18582	0.004	0.2600	No
188	DEFA3	NA	18608	0.004	0.2596	No
189	TLR2	NA	18649	0.003	0.2589	No
190	STAB2	NA	19037	0.000	0.2518	No
191	DEFB103A	NA	19484	0.000	0.2436	No
192	DEFB115	NA	19747	0.000	0.2388	No
193	DEFB105A	NA	20210	0.000	0.2303	No
194	DEFB106A	NA	20276	0.000	0.2291	No
195	DEFB112	NA	20339	0.000	0.2279	No
196	DEFB104B	NA	20602	0.000	0.2231	No
197	DEFB113	NA	21689	0.000	0.2031	No
198	DEFB104A	NA	21882	0.000	0.1996	No
199	LCE3B	NA	21934	0.000	0.1986	No
200	DEFB103B	NA	22111	0.000	0.1954	No
201	DEFB114	NA	23172	0.000	0.1758	No
202	DEFB116	NA	24132	0.000	0.1582	No
203	DEFB105B	NA	24468	0.000	0.1520	No
204	F2RL1	NA	25460	-0.003	0.1338	No
205	NOS2	NA	25752	-0.006	0.1286	No
206	DEFB124	NA	25767	-0.006	0.1284	No
207	IGHA2	NA	25884	-0.007	0.1264	No
208	IL27RA	NA	26246	-0.011	0.1200	No
209	DEFA1	NA	26458	-0.013	0.1164	No
210	PGLYRP1	NA	27022	-0.018	0.1064	No
211	HLA-A	NA	27209	-0.020	0.1034	No
212	PGLYRP2	NA	27626	-0.024	0.0962	No
213	C10orf99	NA	27767	-0.025	0.0941	No
214	LCE3C	NA	28250	-0.030	0.0858	No
215	DEFB128	NA	28284	-0.030	0.0858	No
216	ANXA3	NA	28351	-0.031	0.0852	No
217	FCN2	NA	28546	-0.032	0.0823	No
218	LYST	NA	28803	-0.035	0.0783	No
219	RAB1A	NA	28966	-0.036	0.0760	No
220	LYG2	NA	29063	-0.037	0.0750	No
221	STATH	NA	29227	-0.039	0.0728	No
222	REG3G	NA	29761	-0.044	0.0639	No
223	DEFB1	NA	29780	-0.045	0.0644	No
224	WFDC9	NA	29831	-0.045	0.0644	No
225	BPIFA2	NA	29993	-0.047	0.0624	No
226	WFDC10B	NA	30069	-0.048	0.0620	No
227	IL12B	NA	30171	-0.049	0.0611	No
228	DEFB134	NA	31203	-0.059	0.0433	No
229	SELP	NA	31285	-0.060	0.0430	No
230	TNFRSF1A	NA	31450	-0.061	0.0412	No
231	ANG	NA	31568	-0.062	0.0403	No
232	RAB14	NA	31828	-0.065	0.0368	No
233	CEBPE	NA	31862	-0.065	0.0375	No
234	GRN	NA	32056	-0.067	0.0353	No
235	LPO	NA	32114	-0.068	0.0356	No
236	RNASE7	NA	32270	-0.069	0.0342	No
237	CAMP	NA	32525	-0.072	0.0309	No
238	SHC1	NA	32934	-0.076	0.0250	No
239	DMBT1	NA	33009	-0.077	0.0251	No
240	LCN2	NA	33202	-0.079	0.0232	No
241	ANKRD17	NA	33314	-0.080	0.0228	No
242	COCH	NA	33325	-0.080	0.0242	No
243	TNF	NA	33344	-0.080	0.0254	No
244	MPO	NA	33594	-0.082	0.0225	No
245	HLA-E	NA	33665	-0.083	0.0229	No
246	LYPD8	NA	33986	-0.086	0.0187	No
247	OCIAD1	NA	34550	-0.092	0.0102	No
248	GBP2	NA	34581	-0.092	0.0115	No
249	WFDC11	NA	34610	-0.092	0.0128	No
250	KLK5	NA	34791	-0.094	0.0114	No
251	DEFB110	NA	35310	-0.099	0.0039	No
252	IL23A	NA	35556	-0.102	0.0014	No
253	SEH1L	NA	35875	-0.105	-0.0024	No
254	PI3	NA	36174	-0.108	-0.0057	No
255	PPP1R11	NA	36749	-0.113	-0.0140	No
256	CYBA	NA	37003	-0.116	-0.0163	No
257	C5AR1	NA	37017	-0.116	-0.0142	No
258	MBL2	NA	38004	-0.126	-0.0298	No
259	DEFA1B	NA	38212	-0.129	-0.0311	No
260	IL6	NA	38829	-0.135	-0.0397	No
261	NOTCH2	NA	39157	-0.139	-0.0429	No
262	OPTN	NA	39319	-0.141	-0.0430	No
263	S100A9	NA	39514	-0.143	-0.0437	No
264	S100A12	NA	40126	-0.150	-0.0520	No
265	LYZL6	NA	40212	-0.151	-0.0505	No
266	DEFB127	NA	40641	-0.156	-0.0552	No
267	EPX	NA	40819	-0.158	-0.0553	No
268	WFDC12	NA	41210	-0.163	-0.0592	No
269	TMF1	NA	41427	-0.166	-0.0599	No
270	TLR5	NA	41679	-0.169	-0.0611	No
271	EPHA2	NA	41746	-0.170	-0.0589	No
272	S100A8	NA	41788	-0.170	-0.0562	No
273	LBP	NA	42622	-0.181	-0.0679	No
274	SPINK5	NA	42789	-0.183	-0.0673	No
275	NLRP1	NA	43231	-0.189	-0.0716	No
276	WFDC3	NA	43722	-0.196	-0.0767	No
277	FOXP1	NA	44223	-0.203	-0.0818	No
278	PRG2	NA	44269	-0.204	-0.0785	No
279	CEBPB	NA	44297	-0.204	-0.0749	No
280	KLK3	NA	44383	-0.206	-0.0723	No
281	RBPJ	NA	45918	-0.229	-0.0960	No
282	WFDC2	NA	46744	-0.243	-0.1063	No
283	BCL3	NA	46892	-0.245	-0.1041	No
284	SERPINE1	NA	46977	-0.247	-0.1007	No
285	MAVS	NA	47058	-0.249	-0.0971	No
286	TNFRSF14	NA	47166	-0.250	-0.0941	No
287	TUSC2	NA	47352	-0.253	-0.0924	No
288	MAPKBP1	NA	47432	-0.254	-0.0887	No
289	CXCL6	NA	47701	-0.260	-0.0884	No
290	PPBP	NA	47910	-0.264	-0.0869	No
291	CCL20	NA	48280	-0.271	-0.0883	No
292	GNLY	NA	48334	-0.272	-0.0838	No
293	PLA2G6	NA	48363	-0.273	-0.0788	No
294	GALP	NA	48450	-0.275	-0.0749	No
295	AZU1	NA	48507	-0.276	-0.0704	No
296	ROMO1	NA	48570	-0.277	-0.0659	No
297	TLR9	NA	48781	-0.282	-0.0641	No
298	SLC11A1	NA	48922	-0.285	-0.0610	No
299	OCIAD2	NA	48984	-0.286	-0.0563	No
300	RIPK2	NA	49236	-0.292	-0.0551	No
301	LYG1	NA	49252	-0.292	-0.0495	No
302	RPL39	NA	49811	-0.305	-0.0536	No
303	DEFB123	NA	50115	-0.312	-0.0529	No
304	HMGB2	NA	50313	-0.317	-0.0502	No
305	KLK7	NA	50750	-0.329	-0.0516	No
306	SIRT2	NA	50883	-0.333	-0.0473	No
307	RPL30	NA	51017	-0.337	-0.0430	No
308	IFNE	NA	51596	-0.354	-0.0465	No
309	DROSHA	NA	51687	-0.358	-0.0409	No
310	IGHE	NA	51792	-0.361	-0.0356	No
311	S100A14	NA	51933	-0.366	-0.0308	No
312	ADGRB1	NA	52214	-0.377	-0.0284	No
313	DEFB119	NA	52468	-0.386	-0.0253	No
314	NOD1	NA	52624	-0.392	-0.0202	No
315	LEAP2	NA	52673	-0.394	-0.0132	No
316	MICA	NA	53345	-0.432	-0.0169	No
317	RARRES2	NA	53732	-0.460	-0.0147	No
318	GSDMD	NA	54044	-0.490	-0.0106	No
319	GSDMB	NA	54190	-0.510	-0.0030	No
320	RPS19	NA	54218	-0.515	0.0069	No