Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Thyroid.Thyroid.cls #Thyroid_30-39_versus_Thyroid_70-79.Thyroid.cls #Thyroid_30-39_versus_Thyroid_70-79_repos |
| Phenotype | Thyroid.cls#Thyroid_30-39_versus_Thyroid_70-79_repos |
| Upregulated in class | Thyroid_30-39 |
| GeneSet | GOBP_INSULIN_LIKE_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY |
| Enrichment Score (ES) | 0.4101137 |
| Normalized Enrichment Score (NES) | 1.1139334 |
| Nominal p-value | 0.30998248 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | BMP5 | NA | 197 | 0.407 | 0.0649 | Yes |
| 2 | AR | NA | 302 | 0.376 | 0.1264 | Yes |
| 3 | PIK3R1 | NA | 488 | 0.341 | 0.1805 | Yes |
| 4 | IRS1 | NA | 787 | 0.306 | 0.2267 | Yes |
| 5 | CILP | NA | 1396 | 0.257 | 0.2588 | Yes |
| 6 | GHR | NA | 1815 | 0.236 | 0.2909 | Yes |
| 7 | IGFBP6 | NA | 1926 | 0.231 | 0.3277 | Yes |
| 8 | IGFBP5 | NA | 2427 | 0.212 | 0.3543 | Yes |
| 9 | GHRHR | NA | 2535 | 0.208 | 0.3875 | Yes |
| 10 | IGFBP2 | NA | 3053 | 0.191 | 0.4101 | Yes |
| 11 | EIF2AK3 | NA | 6931 | 0.108 | 0.3572 | No |
| 12 | WNT1 | NA | 10820 | 0.057 | 0.2955 | No |
| 13 | IGFBP3 | NA | 12712 | 0.039 | 0.2674 | No |
| 14 | IGFBP1 | NA | 13126 | 0.036 | 0.2659 | No |
| 15 | GIGYF2 | NA | 13435 | 0.033 | 0.2659 | No |
| 16 | IGF1 | NA | 14153 | 0.028 | 0.2574 | No |
| 17 | PLCB1 | NA | 18640 | 0.004 | 0.1758 | No |
| 18 | MIR1-1 | NA | 20140 | 0.000 | 0.1483 | No |
| 19 | NKX3-1 | NA | 29109 | -0.038 | -0.0097 | No |
| 20 | GHSR | NA | 31254 | -0.059 | -0.0390 | No |
| 21 | BMP2 | NA | 32094 | -0.068 | -0.0430 | No |
| 22 | TRIM72 | NA | 33008 | -0.077 | -0.0468 | No |
| 23 | GH1 | NA | 34547 | -0.092 | -0.0595 | No |
| 24 | IGFBP4 | NA | 34754 | -0.094 | -0.0475 | No |
| 25 | CRIM1 | NA | 39954 | -0.148 | -0.1178 | No |
| 26 | IGF2R | NA | 41190 | -0.163 | -0.1130 | No |
| 27 | ZFAND2B | NA | 47557 | -0.257 | -0.1864 | No |
| 28 | GHRH | NA | 47763 | -0.261 | -0.1462 | No |
| 29 | TSC2 | NA | 48282 | -0.271 | -0.1100 | No |
| 30 | PHIP | NA | 50012 | -0.309 | -0.0896 | No |
| 31 | IGF1R | NA | 50501 | -0.322 | -0.0442 | No |
| 32 | CDH3 | NA | 50649 | -0.326 | 0.0080 | No |
| 33 | AKT1 | NA | 52354 | -0.381 | 0.0410 | No |
