Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Thyroid.Thyroid.cls #Thyroid_30-39_versus_Thyroid_70-79.Thyroid.cls #Thyroid_30-39_versus_Thyroid_70-79_repos |
| Phenotype | Thyroid.cls#Thyroid_30-39_versus_Thyroid_70-79_repos |
| Upregulated in class | Thyroid_30-39 |
| GeneSet | GOBP_PROSTANOID_METABOLIC_PROCESS |
| Enrichment Score (ES) | 0.38018578 |
| Normalized Enrichment Score (NES) | 1.1456223 |
| Nominal p-value | 0.2607143 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | AKR1C1 | NA | 67 | 0.486 | 0.0575 | Yes |
| 2 | AKR1C2 | NA | 95 | 0.466 | 0.1133 | Yes |
| 3 | TBXAS1 | NA | 237 | 0.391 | 0.1580 | Yes |
| 4 | AKR1C3 | NA | 374 | 0.361 | 0.1990 | Yes |
| 5 | CBR1 | NA | 856 | 0.299 | 0.2264 | Yes |
| 6 | PLAA | NA | 913 | 0.294 | 0.2608 | Yes |
| 7 | FABP5 | NA | 1006 | 0.285 | 0.2937 | Yes |
| 8 | AVPR1A | NA | 1472 | 0.253 | 0.3157 | Yes |
| 9 | CYP4F8 | NA | 2029 | 0.227 | 0.3329 | Yes |
| 10 | PTGDS | NA | 2143 | 0.223 | 0.3579 | Yes |
| 11 | HPGDS | NA | 2522 | 0.209 | 0.3761 | Yes |
| 12 | HPGD | NA | 3477 | 0.178 | 0.3802 | Yes |
| 13 | PLA2G3 | NA | 5087 | 0.141 | 0.3677 | No |
| 14 | CD74 | NA | 7865 | 0.094 | 0.3281 | No |
| 15 | PTGS1 | NA | 8064 | 0.091 | 0.3354 | No |
| 16 | PLA2G4A | NA | 9000 | 0.078 | 0.3277 | No |
| 17 | GSTM1 | NA | 9734 | 0.069 | 0.3227 | No |
| 18 | ACOX1 | NA | 13958 | 0.029 | 0.2488 | No |
| 19 | MIR204 | NA | 14204 | 0.028 | 0.2476 | No |
| 20 | CYP2S1 | NA | 15386 | 0.020 | 0.2283 | No |
| 21 | MIR766 | NA | 16074 | 0.015 | 0.2176 | No |
| 22 | EDN1 | NA | 16892 | 0.011 | 0.2040 | No |
| 23 | GSTP1 | NA | 18764 | 0.003 | 0.1700 | No |
| 24 | PTGR1 | NA | 28740 | -0.034 | -0.0087 | No |
| 25 | PNPLA8 | NA | 29168 | -0.038 | -0.0119 | No |
| 26 | PTGIS | NA | 29598 | -0.043 | -0.0146 | No |
| 27 | ANXA1 | NA | 29691 | -0.044 | -0.0111 | No |
| 28 | SIRT1 | NA | 30427 | -0.051 | -0.0184 | No |
| 29 | AKR1C4 | NA | 31350 | -0.060 | -0.0280 | No |
| 30 | TNFRSF1A | NA | 31450 | -0.061 | -0.0224 | No |
| 31 | PLA2G4F | NA | 31565 | -0.062 | -0.0170 | No |
| 32 | IL1B | NA | 35437 | -0.100 | -0.0758 | No |
| 33 | MIR132 | NA | 35454 | -0.100 | -0.0640 | No |
| 34 | PTGES | NA | 36813 | -0.114 | -0.0751 | No |
| 35 | PTGES2 | NA | 39227 | -0.140 | -0.1024 | No |
| 36 | EDN2 | NA | 43523 | -0.193 | -0.1579 | No |
| 37 | MIF | NA | 43879 | -0.198 | -0.1405 | No |
| 38 | PTGR2 | NA | 44117 | -0.202 | -0.1205 | No |
| 39 | DAGLB | NA | 44545 | -0.208 | -0.1032 | No |
| 40 | ATP6V1B1 | NA | 45358 | -0.220 | -0.0915 | No |
| 41 | GSTA1 | NA | 46247 | -0.234 | -0.0795 | No |
| 42 | PTGS2 | NA | 47340 | -0.253 | -0.0690 | No |
| 43 | AVP | NA | 48206 | -0.270 | -0.0522 | No |
| 44 | ZADH2 | NA | 50006 | -0.309 | -0.0478 | No |
| 45 | PTGES3 | NA | 50817 | -0.331 | -0.0227 | No |
| 46 | PIBF1 | NA | 51602 | -0.355 | 0.0058 | No |
| 47 | CES2 | NA | 52896 | -0.406 | 0.0311 | No |
