Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Thyroid.Thyroid.cls #Thyroid_30-39_versus_Thyroid_70-79.Thyroid.cls #Thyroid_30-39_versus_Thyroid_70-79_repos |
| Phenotype | Thyroid.cls#Thyroid_30-39_versus_Thyroid_70-79_repos |
| Upregulated in class | Thyroid_30-39 |
| GeneSet | GOBP_PURINERGIC_NUCLEOTIDE_RECEPTOR_SIGNALING_PATHWAY |
| Enrichment Score (ES) | 0.5228053 |
| Normalized Enrichment Score (NES) | 1.2583604 |
| Nominal p-value | 0.2 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | GPR34 | NA | 58 | 0.496 | 0.0786 | Yes |
| 2 | ADORA3 | NA | 94 | 0.466 | 0.1528 | Yes |
| 3 | P2RY12 | NA | 315 | 0.372 | 0.2086 | Yes |
| 4 | P2RY13 | NA | 379 | 0.359 | 0.2652 | Yes |
| 5 | GPR87 | NA | 903 | 0.294 | 0.3029 | Yes |
| 6 | P2RX3 | NA | 1245 | 0.266 | 0.3395 | Yes |
| 7 | P2RY4 | NA | 1699 | 0.241 | 0.3699 | Yes |
| 8 | GNAT1 | NA | 1810 | 0.236 | 0.4058 | Yes |
| 9 | P2RY8 | NA | 1889 | 0.232 | 0.4417 | Yes |
| 10 | ADCY5 | NA | 2058 | 0.226 | 0.4750 | Yes |
| 11 | PTAFR | NA | 2949 | 0.194 | 0.4898 | Yes |
| 12 | ADORA1 | NA | 4326 | 0.156 | 0.4897 | Yes |
| 13 | P2RX1 | NA | 4404 | 0.155 | 0.5131 | Yes |
| 14 | P2RY14 | NA | 5617 | 0.130 | 0.5118 | Yes |
| 15 | P2RY1 | NA | 6087 | 0.122 | 0.5228 | Yes |
| 16 | P2RY10 | NA | 8580 | 0.083 | 0.4905 | No |
| 17 | P2RX7 | NA | 9074 | 0.077 | 0.4939 | No |
| 18 | P2RX5 | NA | 9075 | 0.077 | 0.5063 | No |
| 19 | ANO6 | NA | 9465 | 0.073 | 0.5108 | No |
| 20 | GPR171 | NA | 10112 | 0.065 | 0.5094 | No |
| 21 | P2RX4 | NA | 25380 | -0.002 | 0.2299 | No |
| 22 | P2RX6 | NA | 26624 | -0.015 | 0.2095 | No |
| 23 | ADA | NA | 27158 | -0.020 | 0.2029 | No |
| 24 | P2RX2 | NA | 30506 | -0.052 | 0.1498 | No |
| 25 | GNAI2 | NA | 34078 | -0.087 | 0.0983 | No |
| 26 | ADORA2B | NA | 35871 | -0.105 | 0.0823 | No |
| 27 | P2RY2 | NA | 40513 | -0.155 | 0.0221 | No |
| 28 | P2RY6 | NA | 48715 | -0.280 | -0.0831 | No |
| 29 | ADORA2A | NA | 50554 | -0.324 | -0.0648 | No |
| 30 | NECAB2 | NA | 52129 | -0.373 | -0.0337 | No |
| 31 | P2RY11 | NA | 54048 | -0.491 | 0.0100 | No |
