Dataset | Thyroid.Thyroid.cls #Thyroid_30-39_versus_Thyroid_70-79.Thyroid.cls #Thyroid_30-39_versus_Thyroid_70-79_repos |
Phenotype | Thyroid.cls#Thyroid_30-39_versus_Thyroid_70-79_repos |
Upregulated in class | Thyroid_30-39 |
GeneSet | GOBP_REGULATION_OF_HUMORAL_IMMUNE_RESPONSE |
Enrichment Score (ES) | 0.71924245 |
Normalized Enrichment Score (NES) | 1.5076044 |
Nominal p-value | 0.056437388 |
FDR q-value | 1.0 |
FWER p-Value | 0.952 |
SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|
1 | C1QC | NA | 22 | 0.551 | 0.0206 | Yes |
2 | C1QA | NA | 28 | 0.541 | 0.0411 | Yes |
3 | C1QB | NA | 33 | 0.534 | 0.0614 | Yes |
4 | C3AR1 | NA | 46 | 0.512 | 0.0807 | Yes |
5 | C5AR2 | NA | 167 | 0.419 | 0.0945 | Yes |
6 | IGHV2-70 | NA | 266 | 0.384 | 0.1073 | Yes |
7 | VSIG4 | NA | 383 | 0.359 | 0.1189 | Yes |
8 | CFP | NA | 562 | 0.330 | 0.1282 | Yes |
9 | IGKV4-1 | NA | 570 | 0.329 | 0.1406 | Yes |
10 | IGHG3 | NA | 685 | 0.317 | 0.1506 | Yes |
11 | IGHV3-11 | NA | 702 | 0.315 | 0.1623 | Yes |
12 | FCGR2B | NA | 799 | 0.305 | 0.1722 | Yes |
13 | IGLV2-23 | NA | 825 | 0.303 | 0.1833 | Yes |
14 | IGHG2 | NA | 846 | 0.301 | 0.1944 | Yes |
15 | C4BPB | NA | 906 | 0.294 | 0.2045 | Yes |
16 | IGKV3-15 | NA | 938 | 0.291 | 0.2150 | Yes |
17 | IGLV3-25 | NA | 962 | 0.289 | 0.2256 | Yes |
18 | IGKV2-40 | NA | 1015 | 0.284 | 0.2355 | Yes |
19 | IGKV2-30 | NA | 1114 | 0.276 | 0.2442 | Yes |
20 | IGHG1 | NA | 1146 | 0.273 | 0.2541 | Yes |
21 | IGKV1-16 | NA | 1158 | 0.272 | 0.2642 | Yes |
22 | IGHV3-30 | NA | 1213 | 0.269 | 0.2735 | Yes |
23 | IGKV1-5 | NA | 1241 | 0.267 | 0.2832 | Yes |
24 | CFHR4 | NA | 1268 | 0.265 | 0.2928 | Yes |
25 | IGLV1-47 | NA | 1327 | 0.261 | 0.3017 | Yes |
26 | IGKV1D-33 | NA | 1341 | 0.260 | 0.3114 | Yes |
27 | IGHV1OR15-1 | NA | 1378 | 0.258 | 0.3205 | Yes |
28 | IGLV3-21 | NA | 1420 | 0.255 | 0.3295 | Yes |
29 | IGLV3-1 | NA | 1435 | 0.255 | 0.3390 | Yes |
30 | IGHV4-59 | NA | 1451 | 0.254 | 0.3484 | Yes |
31 | IGHV3-48 | NA | 1478 | 0.252 | 0.3575 | Yes |
32 | IGHV3-23 | NA | 1510 | 0.251 | 0.3665 | Yes |
33 | IGKV1-12 | NA | 1511 | 0.251 | 0.3761 | Yes |
34 | IGHV2-5 | NA | 1536 | 0.249 | 0.3851 | Yes |
35 | C2 | NA | 1543 | 0.249 | 0.3945 | Yes |
36 | IGHV3-7 | NA | 1550 | 0.248 | 0.4038 | Yes |
37 | IGLV7-43 | NA | 1552 | 0.248 | 0.4133 | Yes |
38 | IGKV3-20 | NA | 1555 | 0.248 | 0.4227 | Yes |
39 | IGLC3 | NA | 1602 | 0.246 | 0.4312 | Yes |
40 | IGLV2-8 | NA | 1729 | 0.239 | 0.4380 | Yes |
41 | IGKV2D-30 | NA | 1768 | 0.238 | 0.4464 | Yes |
42 | IGKV1D-39 | NA | 1794 | 0.236 | 0.4549 | Yes |
43 | IGLV2-11 | NA | 1811 | 0.236 | 0.4636 | Yes |
44 | IGHV4-34 | NA | 1818 | 0.235 | 0.4725 | Yes |
45 | IGHG4 | NA | 1903 | 0.232 | 0.4798 | Yes |
46 | IGLV2-14 | NA | 2033 | 0.227 | 0.4860 | Yes |
47 | IGLV1-51 | NA | 2044 | 0.227 | 0.4945 | Yes |
48 | IGKC | NA | 2057 | 0.226 | 0.5029 | Yes |
49 | IGKV2D-28 | NA | 2099 | 0.225 | 0.5107 | Yes |
50 | IGHV3-13 | NA | 2110 | 0.224 | 0.5191 | Yes |
51 | IGKV1-39 | NA | 2126 | 0.224 | 0.5274 | Yes |
52 | IGLV3-19 | NA | 2132 | 0.224 | 0.5358 | Yes |
53 | IGLV3-27 | NA | 2209 | 0.221 | 0.5428 | Yes |
54 | IGKV5-2 | NA | 2231 | 0.220 | 0.5508 | Yes |
55 | CD5L | NA | 2335 | 0.215 | 0.5571 | Yes |
56 | IGKV3D-20 | NA | 2398 | 0.213 | 0.5641 | Yes |
57 | IGLV1-40 | NA | 2400 | 0.213 | 0.5722 | Yes |
58 | IGHV3-33 | NA | 2419 | 0.212 | 0.5799 | Yes |
59 | IGLC2 | NA | 2547 | 0.208 | 0.5855 | Yes |
60 | IGKV3D-11 | NA | 2573 | 0.207 | 0.5929 | Yes |
61 | IGLC6 | NA | 2574 | 0.207 | 0.6008 | Yes |
62 | CXCL13 | NA | 2612 | 0.205 | 0.6080 | Yes |
63 | IGHV1-69 | NA | 2627 | 0.205 | 0.6155 | Yes |
64 | IGKV2-28 | NA | 2754 | 0.201 | 0.6209 | Yes |
65 | SERPING1 | NA | 2784 | 0.199 | 0.6279 | Yes |
66 | IGKV1-17 | NA | 2814 | 0.199 | 0.6350 | Yes |
67 | IGHV4-39 | NA | 2816 | 0.199 | 0.6425 | Yes |
68 | IGKV1D-12 | NA | 2817 | 0.199 | 0.6501 | Yes |
69 | IGLC1 | NA | 2899 | 0.195 | 0.6560 | Yes |
70 | A2M | NA | 3063 | 0.190 | 0.6603 | Yes |
71 | C9 | NA | 3242 | 0.185 | 0.6641 | Yes |
72 | CR2 | NA | 3270 | 0.184 | 0.6706 | Yes |
73 | IGLV1-44 | NA | 3311 | 0.183 | 0.6768 | Yes |
74 | PROS1 | NA | 3365 | 0.182 | 0.6828 | Yes |
75 | IGHV3-53 | NA | 3723 | 0.172 | 0.6828 | Yes |
76 | FCER2 | NA | 3869 | 0.168 | 0.6865 | Yes |
77 | CFHR1 | NA | 4045 | 0.163 | 0.6895 | Yes |
78 | IGLV6-57 | NA | 4269 | 0.158 | 0.6914 | Yes |
79 | C5 | NA | 4330 | 0.156 | 0.6963 | Yes |
80 | NOD2 | NA | 4498 | 0.152 | 0.6990 | Yes |
81 | IGKV2-29 | NA | 4573 | 0.151 | 0.7034 | Yes |
82 | C4BPA | NA | 4672 | 0.149 | 0.7073 | Yes |
83 | CPB2 | NA | 4984 | 0.143 | 0.7070 | Yes |
84 | LTA | NA | 5001 | 0.142 | 0.7121 | Yes |
85 | ACOD1 | NA | 5098 | 0.140 | 0.7157 | Yes |
86 | CR1 | NA | 5194 | 0.139 | 0.7192 | Yes |
87 | C1QBP | NA | 5767 | 0.127 | 0.7136 | No |
88 | C1S | NA | 5931 | 0.124 | 0.7153 | No |
89 | GATA6 | NA | 6621 | 0.113 | 0.7070 | No |
90 | PGC | NA | 7162 | 0.104 | 0.7010 | No |
91 | IGLC7 | NA | 7419 | 0.100 | 0.7002 | No |
92 | CD19 | NA | 7476 | 0.099 | 0.7029 | No |
93 | CCR7 | NA | 7857 | 0.094 | 0.6995 | No |
94 | C4A | NA | 9029 | 0.078 | 0.6810 | No |
95 | C1R | NA | 10343 | 0.062 | 0.6592 | No |
96 | PTPN6 | NA | 10393 | 0.062 | 0.6607 | No |
97 | CD59 | NA | 10439 | 0.061 | 0.6622 | No |
98 | C6 | NA | 10692 | 0.058 | 0.6598 | No |
99 | PTPRC | NA | 10760 | 0.058 | 0.6607 | No |
100 | CFH | NA | 11950 | 0.046 | 0.6406 | No |
101 | C4B | NA | 12255 | 0.043 | 0.6367 | No |
102 | CFHR5 | NA | 12663 | 0.039 | 0.6307 | No |
103 | C8A | NA | 12895 | 0.038 | 0.6279 | No |
104 | IL17F | NA | 14335 | 0.027 | 0.6025 | No |
105 | C8B | NA | 15305 | 0.020 | 0.5855 | No |
106 | IL17A | NA | 15583 | 0.018 | 0.5811 | No |
107 | F2 | NA | 15633 | 0.018 | 0.5808 | No |
108 | CFHR2 | NA | 15845 | 0.017 | 0.5776 | No |
109 | CPN1 | NA | 18624 | 0.004 | 0.5267 | No |
110 | ZP4 | NA | 18654 | 0.003 | 0.5263 | No |
111 | MIR520E | NA | 23439 | 0.000 | 0.4385 | No |
112 | MIR520B | NA | 24057 | 0.000 | 0.4271 | No |
113 | SPNS2 | NA | 25394 | -0.002 | 0.4027 | No |
114 | C7 | NA | 25876 | -0.007 | 0.3941 | No |
115 | C3 | NA | 26097 | -0.010 | 0.3905 | No |
116 | PHB | NA | 26646 | -0.015 | 0.3810 | No |
117 | CPN2 | NA | 27129 | -0.019 | 0.3729 | No |
118 | CR1L | NA | 32281 | -0.069 | 0.2809 | No |
119 | CD55 | NA | 32929 | -0.076 | 0.2719 | No |
120 | TNF | NA | 33344 | -0.080 | 0.2674 | No |
121 | VTN | NA | 34499 | -0.091 | 0.2497 | No |
122 | KLK5 | NA | 34791 | -0.094 | 0.2479 | No |
123 | CLU | NA | 35202 | -0.098 | 0.2441 | No |
124 | IL1B | NA | 35437 | -0.100 | 0.2436 | No |
125 | ZP3 | NA | 36824 | -0.114 | 0.2225 | No |
126 | C5AR1 | NA | 37017 | -0.116 | 0.2234 | No |
127 | PPP2R3C | NA | 38489 | -0.132 | 0.2014 | No |
128 | FOXJ1 | NA | 38999 | -0.137 | 0.1973 | No |
129 | CFB | NA | 42111 | -0.175 | 0.1468 | No |
130 | CFI | NA | 42287 | -0.177 | 0.1504 | No |
131 | SPINK5 | NA | 42789 | -0.183 | 0.1481 | No |
132 | SUSD4 | NA | 45653 | -0.225 | 0.1041 | No |
133 | C8G | NA | 48988 | -0.286 | 0.0538 | No |
134 | CD81 | NA | 49796 | -0.305 | 0.0506 | No |
135 | HPX | NA | 50642 | -0.326 | 0.0475 | No |
136 | CD46 | NA | 50667 | -0.327 | 0.0595 | No |
137 | KLK7 | NA | 50750 | -0.329 | 0.0705 | No |