Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Thyroid.Thyroid.cls #Thyroid_30-39_versus_Thyroid_70-79.Thyroid.cls #Thyroid_30-39_versus_Thyroid_70-79_repos |
| Phenotype | Thyroid.cls#Thyroid_30-39_versus_Thyroid_70-79_repos |
| Upregulated in class | Thyroid_30-39 |
| GeneSet | GOBP_REGULATION_OF_RECEPTOR_BINDING |
| Enrichment Score (ES) | 0.5017742 |
| Normalized Enrichment Score (NES) | 1.2852173 |
| Nominal p-value | 0.15539305 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.999 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | PLCL2 | NA | 171 | 0.418 | 0.1353 | Yes |
| 2 | GREM2 | NA | 1270 | 0.265 | 0.2028 | Yes |
| 3 | ADIPOQ | NA | 2669 | 0.203 | 0.2445 | Yes |
| 4 | LEF1 | NA | 3379 | 0.181 | 0.2916 | Yes |
| 5 | IL10 | NA | 4670 | 0.149 | 0.3171 | Yes |
| 6 | ANXA2 | NA | 5162 | 0.139 | 0.3541 | Yes |
| 7 | HOXA3 | NA | 5380 | 0.135 | 0.3947 | Yes |
| 8 | LOX | NA | 6410 | 0.116 | 0.4144 | Yes |
| 9 | MMP9 | NA | 6933 | 0.108 | 0.4404 | Yes |
| 10 | ATP2A3 | NA | 7888 | 0.093 | 0.4538 | Yes |
| 11 | HFE | NA | 8353 | 0.086 | 0.4739 | Yes |
| 12 | MIR27B | NA | 8975 | 0.078 | 0.4885 | Yes |
| 13 | NOG | NA | 9546 | 0.072 | 0.5018 | Yes |
| 14 | BDNF | NA | 14355 | 0.026 | 0.4224 | No |
| 15 | ATP2A2 | NA | 16297 | 0.014 | 0.3916 | No |
| 16 | NRP1 | NA | 18349 | 0.005 | 0.3556 | No |
| 17 | B2M | NA | 18477 | 0.004 | 0.3547 | No |
| 18 | MIR148A | NA | 25178 | 0.000 | 0.2319 | No |
| 19 | PLCL1 | NA | 28177 | -0.029 | 0.1865 | No |
| 20 | NKX3-1 | NA | 29109 | -0.038 | 0.1819 | No |
| 21 | ADAM15 | NA | 29677 | -0.043 | 0.1859 | No |
| 22 | RUVBL2 | NA | 34575 | -0.092 | 0.1266 | No |
| 23 | PCSK9 | NA | 38433 | -0.131 | 0.0993 | No |
| 24 | PHLDA2 | NA | 41814 | -0.171 | 0.0938 | No |
| 25 | PTPRF | NA | 53213 | -0.424 | 0.0253 | No |
