Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Thyroid.Thyroid.cls #Thyroid_30-39_versus_Thyroid_70-79.Thyroid.cls #Thyroid_30-39_versus_Thyroid_70-79_repos |
| Phenotype | Thyroid.cls#Thyroid_30-39_versus_Thyroid_70-79_repos |
| Upregulated in class | Thyroid_30-39 |
| GeneSet | GOBP_VASCULAR_ASSOCIATED_SMOOTH_MUSCLE_CONTRACTION |
| Enrichment Score (ES) | 0.45082948 |
| Normalized Enrichment Score (NES) | 1.1197945 |
| Nominal p-value | 0.32604736 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| SYMBOL | TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|
| 1 | ACTA2 | NA | 975 | 0.288 | 0.0746 | Yes |
| 2 | EDNRB | NA | 1742 | 0.239 | 0.1372 | Yes |
| 3 | HTR2A | NA | 1767 | 0.238 | 0.2132 | Yes |
| 4 | EDNRA | NA | 2777 | 0.200 | 0.2588 | Yes |
| 5 | SLC8A1 | NA | 2834 | 0.198 | 0.3214 | Yes |
| 6 | CHRM3 | NA | 3359 | 0.182 | 0.3703 | Yes |
| 7 | DOCK5 | NA | 4359 | 0.156 | 0.4020 | Yes |
| 8 | P2RX1 | NA | 4404 | 0.155 | 0.4508 | Yes |
| 9 | RAP1GDS1 | NA | 6590 | 0.113 | 0.4472 | No |
| 10 | COMP | NA | 10810 | 0.057 | 0.3882 | No |
| 11 | MKKS | NA | 11834 | 0.047 | 0.3845 | No |
| 12 | EDN1 | NA | 16892 | 0.011 | 0.2954 | No |
| 13 | DOCK4 | NA | 18648 | 0.003 | 0.2644 | No |
| 14 | MIR21 | NA | 24232 | 0.000 | 0.1621 | No |
| 15 | CD38 | NA | 26386 | -0.013 | 0.1267 | No |
| 16 | ATP2B1 | NA | 27034 | -0.018 | 0.1208 | No |
| 17 | ADRA2B | NA | 27188 | -0.020 | 0.1244 | No |
| 18 | ARHGAP42 | NA | 34644 | -0.093 | 0.0175 | No |
| 19 | BBS2 | NA | 36068 | -0.107 | 0.0258 | No |
| 20 | PIK3C2A | NA | 37005 | -0.116 | 0.0458 | No |
| 21 | SCNN1B | NA | 39647 | -0.144 | 0.0438 | No |
| 22 | EDN3 | NA | 41280 | -0.164 | 0.0665 | No |
| 23 | EDN2 | NA | 43523 | -0.193 | 0.0874 | No |
| 24 | ZDHHC21 | NA | 51731 | -0.359 | 0.0524 | No |
